This year less than 200 National Library of Medicine indexers expect to index 1 million articles, and this would not be possible without the assistance of the Medical Text Indexer (MTI) system. MTI is an automated indexing system that provides MeSH main heading/subheading pair recommendations to assist indexers with their heavy workload. Over the years, a lot of research effort has focused on improving main heading prediction performance, but automated fine-grained indexing with main heading/subheading pairs has received much less attention. This work revisits the subheading attachment problem, and demonstrates very significant performance improvements using modern Convolutional Neural Network classifiers. The best performing method is shown to outperform the current MTI implementation with a 3.7% absolute improvement in precision, and a 27.6% absolute improvement in recall. We also conducted a manual review of false positive predictions, and 70% were found to be acceptable indexing.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075546 | PMC |
Methods Mol Biol
October 2022
Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products, Russian Academy of Sciences, Moscow, Russia.
An interplay between receptor-binding properties of influenza viruses (IVs) and spectrum of sialic acid-containing receptors on target cells in birds and mammals determine viral host range, tissue tropism, and pathogenicity. Here, we describe method that allows to characterize binding of IVs to biologically relevant cellular receptors using a conventional solid-phase enzyme-linked assay. In this method, we isolate plasma membranes from respiratory and intestinal epithelial cells of animal origin (Subheading 3.
View Article and Find Full Text PDFCurr Pediatr Rev
June 2022
Department of Pediatrics, The University of Calgary, and The Alberta Children's Hospital, Calgary, Alberta, Canada.
Epidermolysis bullosa (EB) is a group of rare congenital genetic conditions that result in painful blistering of the skin and mucous membranes, which occur with minor trauma or friction. There are many types and subtypes of EB that need to be distinguished, as the management and prognosis of each can vary significantly. We aim to perform an up-to-date literature review on congenital EB for healthcare providers in pediatrics.
View Article and Find Full Text PDFAMIA Annu Symp Proc
June 2021
Lister Hill National Center for Biomedical Communications, National Library of Medicine, Bethesda, MD.
This year less than 200 National Library of Medicine indexers expect to index 1 million articles, and this would not be possible without the assistance of the Medical Text Indexer (MTI) system. MTI is an automated indexing system that provides MeSH main heading/subheading pair recommendations to assist indexers with their heavy workload. Over the years, a lot of research effort has focused on improving main heading prediction performance, but automated fine-grained indexing with main heading/subheading pairs has received much less attention.
View Article and Find Full Text PDFEcotoxicol Environ Saf
August 2018
Health Research Institute, Thalassemia and Hemoglobinopathies Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address:
Human impact on the environment leads to the release of many pollutants that produce artificial compounds, which can have harmful effects on the body's endocrine system; these are known as endocrine disruptors (EDs). Nonylphenol (NP) is a chemical compound with a nonyl group that is attached to a phenol ring. NP-induced HAX is a sensitive genotoxic biomarker for detecting possible DNA damage; it also causes male infertility and carcinogenesis.
View Article and Find Full Text PDFMethods Mol Biol
May 2016
Cancer Research Center, 3501 Berrywood Drive, Columbia, MO, 65201, USA,
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!