Magnetic Resonance Imaging Findings in Fetal Corpus Callosal Developmental Abnormalities: A Pictorial Essay.

J Pediatr Neurosci

Department of Fetal Medicine, Mediscan Systems, Chennai, Tamil Nadu, India.

Published: January 2021

The corpus callosum is the principal supratentorial cerebral commissure, which connects the two cerebral hemispheres in the midline. It is divided into rostrum, genu, body, and splenium. Affected patients may develop mental retardation, dysmorphic features, spasticity, ataxia, or epilepsy. Corpus callosal abnormalities may be isolated or be associated with other anomalies such as sulcal abnormality, ventriculomegaly, cerebellar hypoplasia or cerebellar vermian hypoplasia. Magnetic resonance imaging (MRI) plays a major role in the diagnosis of fetal corpus callosal developmental abnormalities when they are suspected on sonography. This pictorial essay shows the MRI findings in fetal corpus callosal developmental abnormalities in a very systematic manner.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078640PMC
http://dx.doi.org/10.4103/jpn.JPN_174_19DOI Listing

Publication Analysis

Top Keywords

corpus callosal
16
fetal corpus
12
callosal developmental
12
developmental abnormalities
12
magnetic resonance
8
resonance imaging
8
findings fetal
8
pictorial essay
8
corpus
5
imaging findings
4

Similar Publications

Article Synopsis
  • Motor symptom laterality in Parkinson's Disease (PD) impacts both motor and nonmotor symptoms, potentially altering patient prognosis, with compensatory mechanisms in the brain's dominant hemisphere playing a key role.
  • This study investigated the microstructural changes in the corpus callosum (CC), the brain's main connector between hemispheres, in 201 right-handed PD patients (split between left- and right-onset) compared to 100 healthy controls using advanced imaging techniques.
  • Findings revealed reduced free water and fractional anisotropy, along with increased mean diffusivity in the CC of patients with left-side PD onset, highlighting the relationship between brain structure and disease symptoms.
View Article and Find Full Text PDF

Background And Aims: The corpus callosum is recognized as the largest interhemispheric white matter structure, coordinating distinct functions of the brain. High-altitude environments may influence the structure of the corpus callosum. This study aims to evaluate the morphologic characteristics of the corpus callosum in Tibetans residing on the Qinghai-Tibet Plateau while investigating the effects of sex, age, and high-altitude exposure on its morphology.

View Article and Find Full Text PDF

Importance: Amidst an unprecedented opioid epidemic, identifying neurobiological correlates of change with medication-assisted treatment of heroin use disorder is imperative. White matter impairments in individuals with heroin use disorder (HUD) have been associated with drug craving, a reliable predictor of treatment outcomes; however, little is known about structural connectivity changes with inpatient treatment and abstinence in individuals with HUD.

Objective: To assess white matter microstructure and associations with drug craving changes with inpatient treatment in individuals with HUD (effects of time and rescan compared with controls).

View Article and Find Full Text PDF

Minimally invasive surgical techniques, such as MR-guided laser interstitial thermal therapy (LITT), have emerged as promising alternatives to open disconnective surgeries in drug-resistant epilepsy (DRE). This review synthesizes current literature on the application of LITT for corpus callosal disconnection and functional hemispheric disconnection. Studies highlight LITT's effectiveness for achieving seizure control and functional outcomes, often with reduced complications compared to traditional open procedures.

View Article and Find Full Text PDF

Microstructurally informed subject-specific parcellation of the corpus callosum using axonal water fraction.

Brain Struct Funct

December 2024

Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, United States.

The corpus callosum (CC) is the most important interhemispheric white matter (WM) structure composed of several anatomically and functionally distinct WM tracts. Resolving these tracts is a challenge since the callosum appears relatively homogenous in conventional structural imaging. Commonly used callosal parcellation methods such as Hofer and Frahm scheme rely on rigid geometric guidelines to separate the substructures that are limited to consider individual variation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!