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| http://dx.doi.org/10.4103/JOC.JOC_133_20 | DOI Listing |
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Rate of testicular histology failure in predicting successful testicular sperm extraction.
Front Endocrinol (Lausanne)
November 2024
Division of Gynecology and Reproductive Medicine, Department of Gynecology, Fertility Center, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Humanitas Research Hospital, Milan, Italy.
Background: The management of Non-Obstructive (NOA) Azoospermia or Obstructive Azoospermia (OA) patients relies on testicular sperm extraction (TESE) followed by intracytoplasmic sperm injection (ICSI). In NOA patients the sperm recovery is successful in only 50% of cases and therefore the ability to predict those patients with a high probability of achieving a successful sperm retrieval would be a great value in counselling the patient and his partner. Several studies tried to suggest predictors of a positive TESE (e.
View Article and Find Full Text PDFSpermatic cord dedifferentiated liposarcoma: Review of literature and case report.
J Pak Med Assoc
August 2024
Department of Radiation Oncology, Combined Military Hospital, Rawalpindi, Pakistan.
Article Synopsis
- A 65-year-old male presented with a tender mass that became non-tender over two months; imaging and fine needle aspiration suggested a spindle cell neoplasm.
- After surgery to remove the tumor, histopathology confirmed it as dedifferentiated liposarcoma, and the patient remains under surveillance with no signs of recurrence after 10 months.
Morphological evaluation of adult domestic cat testicular biopsy after vitrification.
Zygote
June 2024
Laboratory of Wild Animal Biotechnology and Medicine, Faculty of Veterinary Medicine, Federal University of Pará, Castanhal, Pará, Brazil.
Testicular biopsies (9 mm) from domestic cats ( = 10) submitted to orchiectomy were submitted to equilibrium vitrification in the presence of ethylene glycol (EG) alone or combined with dimethylsulfoxide (DMSO) as intracellular cryoprotectants, and sucrose or trehalose as extracellular cryoprotectants. The samples were vitrified with 40% EG or 20% EG + 20% DMSO, plus 0.1 M or 0.
View Article and Find Full Text PDFTiming of Testicular Biopsy in Relation to Oocyte Retrieval and the Outcomes of Intracytoplasmic Sperm Injection.
J Urol
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The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, New York.
Article Synopsis
- The study investigated the timing of microscopic testicular sperm extraction (TESE) in relation to oocyte retrieval and its impact on outcomes of intracytoplasmic sperm injection (ICSI).
- Results showed that sperm retrieval and fertilization rates were lower when TESE was done the day before oocyte retrieval compared to doing it on the same day, but overall embryological and clinical outcomes were similar between both groups.
- The findings suggest that performing micro-TESE before oocyte retrieval allows for better decision-making regarding the procedure without significantly affecting the overall success rates.
A novel sorting method for the enrichment of early human spermatocytes from clinical biopsies.
F S Sci
May 2024
Vancouver Prostate Centre, Vancouver, British Columbia, Canada; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada; Department of Urology, Weill Cornell Medicine, New York, New York. Electronic address:
Article Synopsis
- Scientists wanted to see if they could collect early sperm cells from a human testis biopsy using a special sorting method called FACS.
- They found specific markers (like tags) on the surface of these early sperm cells and used them to identify and sort the cells from a sample taken from three men.
- The results showed that the TSP50 marker could significantly increase the amount of early sperm cells, helping researchers understand and study sperm development better.
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