Infection with SARS-CoV-2 sets off a molecular arms race between virus replication and host cell defense. In this issue of Cell, Flynn, Belk, et al. integrate an advanced large-scale RNA-centered approach with custom CRISPR screens to functionally characterize the interactome of the SARS-CoV-2 RNA genome during infection.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082805 | PMC |
http://dx.doi.org/10.1016/j.cell.2021.04.009 | DOI Listing |
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