ABC-Type Porphyrin SAM on Gold Surface for Bacteria Detection Applications: Synthesis and Surface Functionalization.

Materials (Basel)

Labor für Elektrooptik/Institut für Hochfrequenztechnik, TU Braunschweig, Bienroder Weg 94/Schleinitzstraße 22, D-38106 Braunschweig, Germany.

Published: April 2021

Currently used elaborate technologies for the detection of bacteria can be improved in regard to their time consumption, labor intensity, accuracy and reproducibility. Well-known electrical measurement methods might connect highly sensitive sensing systems with biological requirements. The development of modified sensor surfaces with self-assembled monolayers (SAMs) from functionalized porphyrin for bacteria trapping can lead to a highly sensitive sensor for bacteria detection. Different ABC-type porphyrin structures were synthesized and examined regarding their optical behavior. We achieved the synthesis of a porphyrin for SAM formation on a gold surface as electrode material. Two possible bio linkers were attached on the opposite -position of the porphyrin, which allows the porphyrin to react as a linker on the surface for bacteria trapping. Different porphyrin structures were attached to a gold surface, the SAM formation and the respective coverage was investigated.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070129PMC
http://dx.doi.org/10.3390/ma14081934DOI Listing

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