Application of Capillary Electrophoresis to the Analysis of Bioactive Compounds in Herbal Raw Materials.

Molecules

Department of Toxicology and Bromatology, Faculty of Pharmacy, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, A. Jurasza 2 Street, PL-85089 Bydgoszcz, Poland.

Published: April 2021

AI Article Synopsis

  • The article reviews 16 years of scientific studies (2005-2021) on capillary electrophoresis for analyzing polyphenolic compounds and other substances in teas and plant infusions.
  • Over 60% of the included studies are from China, highlighting a significant contribution from this region.
  • The findings indicate that capillary electrophoresis with UV detection is most common for analyzing flavonoids, while advancements like capillary electrophoresis-mass spectrometry improve sensitivity and could enhance analysis in functional foods.

Article Abstract

The article is a summary of scientific reports from the last 16 years (2005-2021) on the use of capillary electrophoresis to analyze polyphenolic compounds, coumarins, amino acids, and alkaloids in teas or different parts of plants used to prepare aqueous infusions, commonly known as "tea" or decoctions. This literature review is based on PRISMA guidelines and articles selected in base of criteria carried out using PICOS (Population, Intervention, Comparison, Outcome, Study type). The analysis showed that over 60% of articles included in this manuscript comes from China. The literature review shows that for the selective electrophoretic separation of polyphenolic and flavonoid compounds, the most frequently used capillary electromigration technique is capillary electrophoresis with ultraviolet detection. Nevertheless, the use of capillary electrophoresis-mass spectrometry allows for the sensitive determination of analytes with a lower limit of detection and gives hope for routine use in the analysis of functional foods. Moreover, using the modifications in electrochemical techniques allows methods sensitivity reduction along with the reduction of analysis time.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068163PMC
http://dx.doi.org/10.3390/molecules26082135DOI Listing

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