AI Article Synopsis
- The essential oil (EO) of Chiliadenus antiatlanticus, a plant native to southwest Morocco, was analyzed for its chemical composition and biological activities.
- The EO yielded 1.07% and contained 27 metabolites, with camphor, borneol, and intermedeol being the primary components.
- It exhibited antibacterial properties against 24 out of 71 strains (mostly Gram-positive) and showed significant cytotoxic effects on liver and melanoma tumor cell lines at a concentration of 100 μg/mL.
Article Abstract
The chemical composition and in vitro antibacterial and cytotoxic activities of the essential oil (EO) of Chiliadenus antiatlanticus (Emb. & Maire) Gómiz, an asteraceous species endemic to the southwest of Morocco, were investigated. The EO yield was 1.07±0.28 %, twenty-seven metabolites were identified representing more than 96.4 % of the total composition. Camphor (35.7 %) and derivatives, borneol (4.9 %) and camphene (4.2 %) together with intermedeol (19.9 %), α-pinene (15.5 %) and (E)-pinocarveol (4.1 %) were the major constituents. An antibacterial activity was noticed against 24 strains (all Gram-positive) out of 71 at MICs values=100 μg/mL. The EO also showed significant toxicity towards liver HepG2 (55.8 % of cell viability) and melanoma B16 4A5 (41.6 % of cell viability) tumor cell lines at 100 μg/mL.
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| http://dx.doi.org/10.1002/cbdv.202100115 | DOI Listing |
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