AI Article Synopsis
- - The study focused on comparing the immunoexpression levels of RANK, RANKL, and OPG in three types of dental cysts: dentigerous cysts, odontogenic keratocysts, and ameloblastomas, using data from various databases and adhering to specific study criteria.
- - A comprehensive analysis revealed that dentigerous cysts and odontogenic keratocysts exhibited a higher OPG to RANKL ratio, suggesting a less aggressive nature, whereas ameloblastomas showed a significantly higher RANKL in comparison to OPG, indicating a more aggressive behavior.
- - Out of nine studies included, most demonstrated a moderate risk of bias, with findings pointing to the aggressive potential of ameloblastoma
Article Abstract
The aim of this study was to assess and compare RANK, RANKL, and OPG immunoexpression in dentigerous cyst, odontogenic keratocyst, and ameloblastoma. The protocol was registered in PROSPERO (CRD42018105543). Seven databases (Embase, Lilacs, LIVIVO, PubMed, Scopus, SciELO, and Web of Science) were the primary search sources and two databases (Open Grey and Open Thesis) partially captured the "grey literature". Only cross sectional studies were included. The JBI Checklist assessed the risk of bias. A meta-analysis with random effects model estimated the values from the OPG and RANKL ratio reported by the individual studies and respective 95% confidence intervals. The heterogeneity among studies was assessed with I2 statistics. Only nine studies met the inclusion criteria and were considered in the analyses. The studies were published from 2008 to 2018. Two studies presented low risk of bias, while seven studies presented moderate risk. The meta-analysis showed the highest OPG>RANKL ratio for dentigerous cyst (ES=43.3%; 95% CI=14.3-74.8) and odontogenic keratocyst (ES=36.8%; 95% CI=18.8-56.7). In contrast, the highest OPG
Download full-text PDF
Source
http://dx.doi.org/10.1590/0103-6440202103387 DOI Listing Publication Analysis
Top Keywords
Similar Publications
Oral surgery complication resulting from undiagnosed common variable immunodeficiency: a case report.
Oral Maxillofac Surg
December 2024
Universidade Federal de Goiás, Goiânia, Brazil.
Purpose: This report aims to present an interdisciplinary approach to diagnosing and treating a case of Common Variable Immunodeficiency (CVID), an inborn error of immunity, resulting in successive complications following a third molar extraction procedure.
Case Presentation: The patient, a 37-year-old Caucasian female, sought a specialist for the extraction of an impacted lower third molar associated with dentigerous cyst. Due to the possibility of mandibular fracture, a bone fixation system was used in the region.
Management of Infected Dentigerous Cyst in an 8-year-old Patient Using Decompression Technique: A Case Report and Review of Literature.
Int J Clin Pediatr Dent
October 2024
Department of Public Health Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Article Synopsis
- Odontogenic cysts can be treated aggressively through enucleation or conservatively through techniques like cyst decompression.
- Cyst decompression helps to alleviate pressure within the cyst, leading to its shrinkage and potentially avoiding more invasive treatments.
- The article details a case study of an 8-year-old boy with an infected odontogenic cyst who underwent a decompression technique for treatment.
Application of Radiomics Features in Differential Diagnosis of Odontogenic Cysts.
Dentomaxillofac Radiol
November 2024
Selcuk University Faculty of Dentistry, Oral and Maxillofacial Radiology Department, Konya, 42130, Turkiye.
Article Synopsis
- The study aimed to differentiate between radicular cysts (RCs), dentigerous cysts (DCs), and odontogenic keratocysts (OKCs) using radiomic features as a non-invasive diagnosis method before surgery.
- A total of 161 cysts were analyzed through semi-automatic segmentation of CBCT images, focusing on various shape-based and textural features to assess their differences.
- Results indicated significant statistical differences in radiomic features among the cyst types, suggesting these features could help with differential diagnosis without needing a biopsy.
Analysis of Germline and Somatic Mutation in Patients With Developmental Odontogenic Cysts Using Targeted Gene Panel.
J Oral Pathol Med
November 2024
Department of Biochemistry, Tokyo Dental College, Chiyoda-ku, Tokyo, Japan.
Background: Odontogenic keratocyst (OKC) is a partial manifestation of Gorlin syndrome (GS), resulting from the abnormal activation of the hedgehog signaling pathway. OKC predominantly occurs in young adults and is mostly asymptomatic at the time of initial diagnosis. As OKC is asymptomatic, GS can be challenging to diagnose in certain instances.
View Article and Find Full Text PDFA Case of a Dentigerous Cyst with a Malformed Tooth in the Mandible of a Child.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Oral and Maxillofacial Surgery, Institute of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki 305-8575 Japan.
This study reports a rare case of a dentigerous cyst in a malformed tooth in the mandible of a 5-year-old Japanese boy. Panoramic radiography revealed a cystic lesion with hard tissues inside. The patient underwent surgery under general anesthesia.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!