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Many faces of cutaneous leishmaniasis.
Postgrad Med J
September 2024
Department of Medical Microbiology, Harran University Medical Faculty, Şanlıurfa 63000, Turkey.
Article Synopsis
- This study aimed to identify atypical clinical presentations of cutaneous leishmaniasis (CL) in Şanlıurfa province, encompassing a retrospective analysis of 213 patients with non-standard symptoms out of 1,751 diagnosed cases between 2019 and 2022.
- The prevalence of atypical CL was found to be 12.1%, with common atypical lesions including lupoid, erysipeloid, and impetiginous types, along with many others resembling various skin conditions and diseases.
- The research highlights that CL can mimic a wide range of infectious, inflammatory, and neoplastic disorders, stressing the importance of thorough differential diagnosis for persistent non-healing skin lesions, especially in areas where CL is
Background: Lymphatic malformations (LMs) often pose treatment challenges due to a large size or a critical location that could lead to disfigurement, and there are no standardized treatment approaches for either refractory or unresectable cases.
Methods: We examined the genomic landscape of a patient cohort of LMs ( = 30 cases) that underwent comprehensive genomic profiling using a large-panel next-generation sequencing assay. Immunohistochemical analyses were completed in parallel.
Kaposi Sarcoma-Like Lesions Caused by Infection in a Kidney Transplant Patient.
Ann Dermatol
February 2021
Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Multiple Eruptive Epithelioid Hemangiomas: A Subset of Cutaneous Cellular Epithelioid Hemangioma With Expression of FOS-B.
Am J Surg Pathol
January 2019
Dermatopathology Department, Dermatopathologie Friedrichshafen, Friedrichshafen, Germany.
There is a wide clinicopathologic spectrum of vascular proliferations characterized by the presence of epithelioid endothelial cells, comprising epithelioid hemangioma (EH)-pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma (PM-HAE), epithelioid hemangioendothelioma, and epithelioid angiosarcoma. Immunohistochemical FOS-B expression as well as FOS-B rearrangement (fluorescent in situ hybridization [FISH]) have recently been described as diagnostically relevant underpinnings of EH (restricted to osseous lesions) and PM-HAE. The aim of this study was to clinicopathologically characterize and to elucidate FOS-B expression in patients with eruptive lesions of the cellular variant of cutaneous EH.
View Article and Find Full Text PDFEvidence for Kaposi Sarcoma Originating from Mesenchymal Stem Cell through KSHV-induced Mesenchymal-to-Endothelial Transition.
Cancer Res
January 2018
Institute of Human Virology and Ministry of Education Key Laboratory of Tropical Disease Control, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China.
The major transmission route for Kaposi sarcoma-associated herpesvirus (KSHV) infection is the oral cavity through saliva. Kaposi sarcoma (KS) frequently occurs in the oral cavity in HIV-positive individuals and is often the first presenting sign of AIDS. However, the oral target cells for KSHV infection and the cellular origin of Kaposi sarcoma remain unknown.
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