Pirfenidone-Induced Lichenoid Drug Eruption in a Patient with Idiopathic Lung Fibrosis.

Ann Dermatol

Department of Dermatology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.

Published: February 2019

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7992701PMC
http://dx.doi.org/10.5021/ad.2019.31.1.103DOI Listing

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Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and lethal lung disease characterized by progressive dyspnea and irreversible loss of lung function. Pirfenidone is a novel anti-fibrotic and anti-inflammatory drug, which reduces deterioration in the lung function and prolongs progression-free survival in patients with IPF. However, it has adverse effects including gastrointestinal symptoms, hepatic dysfunction or skin photosensitivity, and rash.

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