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| http://dx.doi.org/10.5021/ad.2018.30.6.739 | DOI Listing |
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A Chlorin e6 derivative-mediated photodynamic therapy versus doxycycline for moderate-to-severe rosacea: A prospective, randomized, controlled study.
Photodiagnosis Photodyn Ther
January 2025
Institute of Photomedicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, 200443, China. Electronic address:
Background: Photodynamic therapy (PDT) is beneficial for managing rosacea, and chlorin e6 derivative-mediated photodynamic therapy (STBF-PDT) has demonstrated efficacy in reducing acne lesions with mild adverse reactions.
Objectives: This study aimed to assess the effectiveness and safety of STBF-PDT for the treatment of moderate-to-severe rosacea.
Methods: In this prospective, randomised, evaluator-blind controlled study, patients with moderate-to-severe rosacea were assigned to receive up to six STBF-PDT sessions or 100 mg of doxycycline daily for eight weeks, followed by a 24-week follow-up.
A comparative study between fractional microneedling radiofrequency with systemic isotretinoin and fractional microneedling alone in the treatment of rosacea.
Postepy Dermatol Alergol
October 2024
Department of Dermatology, AL-Hakim General Hospital, Baghdad, Iraq.
Introduction: Rosacea is a chronic inflammatory disease presenting with facial flushing, non-transient erythema, papules/pustules, telangiectasia, and phymatous changes. Secondary manifestations, such as itching, burning, or stinging, are often observed in patients with rosacea. The pathogenesis of rosacea is not fully understood, but immune dysfunction, Demodex infection, neurovascular dysregulation, and exposure to ultraviolet radiation represent contributing factors.
View Article and Find Full Text PDFEvaluating the Efficacy of Oral Ivermectin on Clinical Symptoms and x Densities in Patients with Demodicosis.
Drug Des Devel Ther
November 2024
School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.
Article Synopsis
- Dermatologists struggle with treating demodicosis due to its recurrence and difficulty in normalizing densities even after improvement.
- The study evaluated the effectiveness of oral ivermectin (200 µg/kg/week) in improving clinical symptoms and reducing density in 40 demodicosis patients, comparing those with lower and higher densities.
- Results showed 75% of patients achieved clinical remission, with quicker remission for patients with lower densities (28 days) compared to those with higher densities (56 days).
Epidemiology and Healthcare of Juvenile and Late-Onset Acne: Claims Data Analysis.
Dermatol Ther (Heidelb)
November 2024
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany.
Article Synopsis
- * The study found significant differences in skin and non-skin-related comorbidities among those with acne, particularly in adults, with the majority receiving treatment from dermatologists and prescribed systemic therapies like anti-infectives and retinoids.
- * Results indicate that acne management in Germany is common but often does not adhere to established medical guidelines, highlighting a need for improved treatment protocols.
Ferulic Acid in the Treatment of Papulopustular Rosacea: A Randomized Controlled Study.
J Cosmet Dermatol
January 2025
Department of Dermatology, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong, China.
Background: Rosacea is a chronic inflammatory skin disease characterized by flushing, erythema, papules, and pustules on the central face. It affects patient appearance and is noted for its chronicity, recurrence, and resistance to treatment. Effective rosacea treatment requires repairing the skin barrier, reducing inflammation, and promoting vasoconstriction.
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