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Curr Dev Nutr
September 2024
Unidad de Biologia Molecular y Medicina Genomica, Insituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.
Background: A risk haplotype in characterized by alterations in fatty acid metabolism emerged as a genetic risk factor associated with increased susceptibility to type 2 diabetes (T2D) in Mexican population. Its role on treatment responses is not well understood.
Objectives: We aimed to determine the impact of the risk haplotype on the metabolomic profile during a lifestyle intervention (LSI).
Spectrochim Acta A Mol Biomol Spectrosc
May 2024
Centro de Química Inorgánica (CEQUINOR-CONICET-UNLP- Asoc CICPBA)-Departamento de Química-Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Boulevard 120 entre 60 y 64, C.C.962- (B1900AVV) -1900 La Plata, Argentina. Electronic address:
L-Acetylcarnitine (ALC), a versatile compound, has demonstrated beneficial effects in depression, Alzheimer's disease, cognitive impairment, and other conditions. This study focuses on its antithyroid activity. The precursor molecule, L-carnitine, inhibited the uptake of triiodothyronine (T3) and thyroxine (T4), and it is possible that ALC may reduce the iodination process of T3 and T4.
View Article and Find Full Text PDFJ Ethnopharmacol
April 2024
Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Egypt. Electronic address:
Ethnopharmacological Relevance: Saussurea costus (Falc.) Lipschitz. is one of the most reputed medicinal plants as a traditional medicine in the Arab and Middle East regions in the treatment of thyroid disorders, however, more investigations are needed to fully understand its effectiveness and mechanism of action.
View Article and Find Full Text PDFExpert Opin Pharmacother
January 2024
Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
J Med Case Rep
February 2023
Anestesia and Intensive Care Unit, Pescara General Hospital, Via Fonte Romana, 8, 65124, Pescara, PE, Italy.
Background: Undesired intrathecal injections represent an important subset of medical errors, albeit rare. Clinical effects depend on the type and concentration of drug(s) injected. Here we report on the case of a healthy woman with persistent low back pain, treated with a paravertebral injection of lidocaine, thiocolchicoside, and L-acetylcarnitine at an orthopedic practice.
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