Using intergenerational, prospective data at ages 9 months, 7, 11, and 14 years from the nationally representative United Kingdom Millennium Cohort Study, this interdisciplinary study unpacks why 14-year-old adolescents with early perceived pubertal timing (PT) were more likely to drink alcohol (ever, frequent, and binge drinking) compared to those whose PT was on-time or late (5,757 girls, 5,799 boys; 80% White, 10% Asian, 3% Black, and 7% Other British). Parents allowed drinking among 22% (18%) of early PT girls (boys) compared to 11% of late PT adolescents; formal mediation models showed differences by PT in parent permissiveness and gains in alcohol-using friends primarily explained age 14 PT-drinking associations. Parental alcohol permissiveness should be a key prevention target for early PT adolescents.
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http://dx.doi.org/10.1111/cdev.13569 | DOI Listing |
Children (Basel)
January 2025
Department of Pediatrics, Division of Pediatric Endocrinology, Demiroğlu Bilim University, 34394 Istanbul, Türkiye.
This review examines the inconsistent effects of endocrine-disrupting chemicals (EDCs) and pollutants on pubertal timing, emphasizing the methodological challenges contributing to variability in findings. Data from nine key studies reveal that chemicals such as BPA, phthalates, and PFAS impact pubertal onset differently based on exposure timing, dosage, and sex. For instance, BPA is linked to earlier puberty in girls but delayed onset in boys, while other EDCs show mixed effects across populations.
View Article and Find Full Text PDFRes Child Adolesc Psychopathol
January 2025
Department of Psychology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Developmental changes in youth sleep preferences (chronotype) and pubertal development are consequential for youth risk for depression. Previous research has identified individual differences in chronotype in risk for psychopathology. However, little is known regarding how the timing of chronotype may confer risk in youth.
View Article and Find Full Text PDFMol Cell Endocrinol
January 2025
Department of Molecular Genetics, Function and Therapy, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus. Electronic address:
Background And Aims: Puberty is a crucial developmental stage marked by the transition from childhood to adulthood, organized by complex hormonal signaling within the neuroendocrine system. The hypothalamus, a central region in this system, regulates pubertal functions through the hypothalamic-pituitary-gonadal (HPG) axis. Gonadotropin-releasing hormone (GnRH) neurons, essential in puberty control, release GnRH in a pulsatile manner, initiating the production of sex hormones.
View Article and Find Full Text PDFJ Endocr Soc
January 2025
Cellular and Molecular Endocrinology Laboratory LIM/25, Division of Endocrinology and Metabolism, Clinicas Hospital, School of Medicine, University of Sao Paulo, 01246-903 Sao Paulo, Brazil.
Human puberty is a dynamic biological process determined by the increase in the pulsatile secretion of GnRH triggered by distinct factors not fully understood. Current knowledge reveals fine tuning between an increase in stimulatory factors and a decrease in inhibitory factors, where genetic and epigenetic factors have been indicated as key players in the regulation of puberty onset by distinct lines of evidence. Central precocious puberty (CPP) results from the premature reactivation of pulsatile secretion of GnRH.
View Article and Find Full Text PDFAm Psychol
January 2025
Department of Psychology, University of Minnesota, Twin Cities.
Sexual minority adolescents experience puberty earlier than their heterosexual peers. Early puberty is an indicator of premature aging and can be partly driven by chronic stress linked to discrimination. Nonetheless, the neural, cognitive, and social development linked to puberty enables adolescents to explore and understand their sexual identities.
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