Background: Percutaneous coronary intervention (PCI) in patients with unprotected left main coronary artery disease (ULMCAD) is increasing strategy in coronary artery patients. However, there is a lack of knowledge on the impact of sex on outcomes of patients undergoing ULMCAD PCI.
Methods: From January 2004 to December 2015, there were 3,960 patients undergoing ULMCAD PCI at our institution, including 3,121 (78.8%) men and 839 (21.2%) women. The clinical outcome included the incidence of major adverse cardiac events (MACE) (the composite of all-cause death, myocardial infarction (MI), and revascularization), all-cause death, MI, revascularization at three years follow-up.
Results: Compared with men, women had not significantly different MACE (14.7% . 14.6%, = 0.89, all-cause death (3.5% . 3.7%, = 0.76), MI (5.0% . 4.3%, = 0.38), revascularization (9.1% . 8.9%, = 0.86), respectively. After adjustment, rates of MACE (HR = 1.49; 95% CI: 1.24-1.81; < 0.0001) and all-cause death (HR = 1.65; 95% CI: 1.09-2.48; = 0.017) occurred more frequently in male patients, as well as revascularization (HR = 1.46; 95% CI: 1.16-1.85; = 0.001).
Conclusion: In this analysis, compared to men, women undergoing ULMCAD PCI have better outcomes of MACE, all-cause death, and revascularization.
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| http://dx.doi.org/10.11909/j.issn.1671-5411.2021.03.004 | DOI Listing |
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