AI Article Synopsis

  • Two new alkylated tetronic acid derivatives, ardisiatetrons A and B, were discovered from the leaves of Ardisia quinquegona, along with four triterpenoids and one known compound.
  • The structure of one of the new triterpenes was confirmed through X-ray crystallography.
  • Compounds 2, 3, and 7 exhibited moderate activity against Leishmania and showed cytotoxic effects on A549 cells.

Article Abstract

From the leaves of Ardisia quinquegona, two alkylated tetronic acid derivatives, named ardisiatetrons A and B (1, 2), and four triterpenoids (3-6) were isolated together with one known compound (7) by a combination of various kinds of chromatography. The structure of new methyl migrated triterpene (3) was confirmed by X-ray crystallographic analysis. Compounds 2, 3, and 7 showed moderate anti-Leishmania activity and cytotoxicity towards A549 cells.

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Source
http://dx.doi.org/10.1007/s11418-021-01513-1DOI Listing

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