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Background: Multi-professional obstetric emergencies training is one promising strategy to improve maternity care. Sustaining training programmes following successful implementation remains a challenge. Understanding, and incorporating, key components within the implementation process can embed interventions within healthcare systems, thereby enhancing sustainability. This study aimed to identify key components influencing sustainability of PRactical Obstetric Multi-Professional Training (PROMPT) in the Philippines, a middle-income setting.
Methods: Three hospitals were purposively sampled to represent private, public and teaching hospital settings. Two focus groups, one comprising local trainers and one comprising training participants, were conducted in each hospital using a semi-structured topic guide. Focus groups were audio recorded. Data were analysed using thematic analysis. Three researchers independently coded transcripts to ensure interpretation consistency.
Results: Three themes influencing sustainability were identified; attributes of local champions, multi-level organisational involvement and addressing organisational challenges.
Conclusions: These themes, including potential barriers to sustainability, should be considered when designing and implementing training programmes in middle-income settings. When 'scaling-up', local clinicians should be actively involved in selecting influential implementation champions to identify challenges and strategies specific to their organisation. Network meetings could enable shared learning and sustain enthusiasm amongst local training teams. Policy makers should be engaged early, to support funding and align training with national priorities.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077832 | PMC |
http://dx.doi.org/10.1186/s12913-021-06385-5 | DOI Listing |
Health Res Policy Syst
December 2024
Health Information System, World Health Organization (WHO) Regional Office for Africa, Brazzaville, Republic of Congo.
Background: There is widespread enthusiasm for scaling interventions to strengthen health systems. However, little is known about the scalability of such interventions in Africa. In this study, we seek to assess the scalability of interventions for improving the functionality of health systems in Africa, as a key to large-scale implementation strategy of interventions with potential for impact.
View Article and Find Full Text PDFHealth Res Policy Syst
December 2024
Ecole de Santé Publique, Université Libre de Bruxelles, Brussels, Belgium.
Background: In South Kivu (Eastern Democratic Republic of the Congo [DRC]), health districts (HDs) affected by chronic armed conflicts are devising coping mechanisms to continue offering healthcare services to the population. Nonetheless, this alone does not suffice to make them fully resilient to such conflicts. This study aims to explore the characteristics of these HDs' resilience.
View Article and Find Full Text PDFSci Rep
December 2024
College of Mechanical Engineering, Beihua University, Jilin City, Jilin, 132021, China.
To address the limitations of weak information extraction of rolling bearing fault features and the poor generalization performance of diagnostic methods, a novel method was proposed based on sparrow search algorithm (SSA)-Variational Mode Decomposition (VMD) and refined composite multi-scale dispersion entropy (RCMDE). Firstly, SSA optimized the key parameters of VMD to decompose the fault signal. The time-frequency domain comprehensive evaluation factor algorithm was then employed to select the sensitive intrinsic mode function (IMF) components for reconstruction.
View Article and Find Full Text PDFRNA Biol
December 2025
Paracrine Therapeutics Pte. Ltd, Tai Seng Exchange, Singapore, Singapore.
Mesenchymal Stromal/Stem Cells (MSCs) are among the most frequently studied cell types in clinical trials, and their small extracellular vesicles (sEVs) are now being extensively investigated for therapeutic applications. The RNA cargo of MSC-sEVs, particularly miRNAs and mRNAs, is widely believed to be a key therapeutic component of these vesicles. In this review, we critically examine using first principles and peer-reviewed literature, whether MSC- extracellular vesicles (MSC-EVs) can deliver sufficient quantity of functional miRNA or mRNA to target compartments within recipient cells to elicit a pharmacological response.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Beijing Key Laboratory of Lignocellulosic Chemistry, MOE Engineering Research Center of Forestry Biomass Materials and Bioenergy, Beijing Forestry University, Beijing 100083, China. Electronic address:
Technical alkaline lignin (TAL)-based composite films have been developed for anti-corrosion applications, during which one-component solvents, including acetone and ethanol, were employed. The poor solubility of TAL in the abovementioned solvents undoubtedly resulted in inhomogeneous surface micromorphology and the consequent unstable performance. The present study provides a series of ethylcellulose/TAL (EC/TAL) composite films with uniform surface microstructure by using the 1,4-Dioxane/water binary solvent.
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