Objectives: In Turkey, the genus Lehm. is represented by two species, namely Boiss. and (Willd.) Lehm., which are used as both food and for medicinal purposes. This study aimed to evaluate the antidiabetic and antioxidant potential and phytochemical profiles of leaf, flower, and root extracts of species.
Materials And Methods: α-Glucosidase and α-amylase inhibitory activities, antioxidant effects, and total phenol and flavonoid contents of extracts were evaluated. High-performance liquid chromatography was performed for identifying and quantifying phenolic compounds, which are responsible for various activities of these extracts.
Results: Among the investigated phenolic compounds, caffeic and rosmarinic acids and rutin were determined and quantified in methanol extracts. Rutin was the major compound in the flower extract of . Rutin and rosmarinic acid were the major compounds in the leaf extract of . The flowers, leaves and roots of were also rich in rosmarinic acid. The antioxidant and antidiabetic potential of these extracts may be attributable to their rutin and rosmarinic acid content.
Conclusion: species can be used as natural sources of antioxidants. Notably, extracts can be used for the development of herbal products with antidiabetic potential.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100787 | PMC |
http://dx.doi.org/10.4274/tjps.galenos.2020.12258 | DOI Listing |
Discov Oncol
January 2025
Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, No. 58, Yuelu District, Changsha, 410006, Hunan, China.
Objective: Rosmarinic acid (RosA) is a natural polyphenol compound that has been shown to be effective in the treatment of inflammatory disease and a variety of malignant tumors. However, its specific mechanism for the treatment of lung adenocarcinoma (LUAD) has not been fully elucidated. Therefore, this study aims to clarify the mechanism of RosA in the treatment of LUAD by integrating bioinformatics, network pharmacology and in vivo experiments, and to explore the potential of the active ingredients of traditional Chinese medicine in treating LUAD.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
December 2024
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(UPLC-Q-TOF-MS/MS) was used to rapidly identify the chemical components in Dracocephalum moldavica, and UPLC was employed to determine the content of its main components. MS analysis was performed using an electrospray ionization(ESI) source and data were collected in the negative ion mode. By comparing the retention time and mass spectra of reference compounds, and using a self-built compound database and the PubChem database, 68 compounds were identified from D.
View Article and Find Full Text PDFAppl Physiol Nutr Metab
January 2025
Brock University, Department of Health Sciences, St Catharines, Ontario, Canada.
The worldwide epidemic of obesity has drastically worsened with the increase in more sedentary lifestyles and increased consumption of fatty foods. Increased blood free fatty acids (FFAs), often observed in obesity, leads to impaired insulin action, and promotes the development of insulin resistance and Type 2 diabetes mellitus (T2DM). JNK, IKK-NF-κB, and STAT3 are known to be involved in skeletal muscle insulin resistance.
View Article and Find Full Text PDFJ Med Food
January 2025
Integrative Skin Science and Research, Sacramento, California, USA.
Photoprotective effects of various nutritional components and supplements have been demonstrated in animal and studies. The objective of this systematic review is to assess the photoprotective effects of various dietary supplements. A systematic review of studies assessing dietary supplements on photoprotective outcomes was performed.
View Article and Find Full Text PDFFood Chem X
January 2025
National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan.
Unlabelled: This study investigates the optimization of bioactive components in thermosonicated black carrot juice using response surface methodology (RSM) and gradient boosting (GB) modeling techniques. Thermosonication, a combination of ultrasound and heat, was applied to enhance the nutritional quality of black carrot juice, which is rich in anthocyanins, phenolic compounds, and antioxidants. The study examined the effects of temperature, processing time, and ultrasonic amplitude on total carotenoid content (TCC), total anthocyanin content (TAC), ferric reducing antioxidant power (FRAP), and total phenolic content.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!