Objectives: In Turkey, the genus Lehm. is represented by two species, namely Boiss. and (Willd.) Lehm., which are used as both food and for medicinal purposes. This study aimed to evaluate the antidiabetic and antioxidant potential and phytochemical profiles of leaf, flower, and root extracts of species.

Materials And Methods: α-Glucosidase and α-amylase inhibitory activities, antioxidant effects, and total phenol and flavonoid contents of extracts were evaluated. High-performance liquid chromatography was performed for identifying and quantifying phenolic compounds, which are responsible for various activities of these extracts.

Results: Among the investigated phenolic compounds, caffeic and rosmarinic acids and rutin were determined and quantified in methanol extracts. Rutin was the major compound in the flower extract of . Rutin and rosmarinic acid were the major compounds in the leaf extract of . The flowers, leaves and roots of were also rich in rosmarinic acid. The antioxidant and antidiabetic potential of these extracts may be attributable to their rutin and rosmarinic acid content.

Conclusion: species can be used as natural sources of antioxidants. Notably, extracts can be used for the development of herbal products with antidiabetic potential.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100787PMC
http://dx.doi.org/10.4274/tjps.galenos.2020.12258DOI Listing

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