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| http://dx.doi.org/10.1164/rccm.202104-0844ED | DOI Listing |
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Effect of Flow Rates of High-flow Nasal Cannula on Extubation Outcomes: A Randomized Controlled Trial.
Chest
December 2024
From the Division of Pulmonary and Critical Care Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Background: High-flow nasal cannula (HFNC) has emerged as a promising intervention for post-extubation oxygen therapy, with the potential to reduce the need for reintubation. However, it remains unclear whether using a higher flow setting provides better outcomes than the commonly used flow rate of 30-50 L/min.
Research Question: Does setting the flow rate of HFNC at 60 L/min versus 40 L/min for post-extubation care result in different extubation outcomes?
Study Design And Methods: This randomized controlled trial assigned intubated patients to receive HFNC at either a 60 L/min or 40 L/min flow rate following extubation.
Endoscopic Screening for Laryngotracheal Complications in Children Following Prolonged Mechanical Ventilation Maintained Through Endotracheal Intubation: A Cross-Sectional Pilot Project.
Ann Otol Rhinol Laryngol
December 2024
Department of Otorhinolaryngology & Head-Neck Surgery, Medical College & Hospital, Kolkata; West Bengal, India.
Background: An endoscopic screening program following successful weaning from prolonged mechanical ventilation maintained through endotracheal tube (ET; ) may be justified to assess the upper (laryngotracheal) airway in children who may not always be symptomatic for intubation-related complications.
Objectives: To evaluate effects of prolonged intubation in children through endoscopic screening of the laryngotracheal airway.
Methods: In this cross-sectional pilot project, children (2 months-12 years) successfully extubated following prolonged intubation were selected, irrespective of having symptoms, for a 1-time flexible nasolaryngoscopy at third to sixth month post-extubation (follow-up window).
Negative pressure pulmonary edema: a case report and literature review.
Front Med (Lausanne)
December 2024
Department of Emergency Medicine, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
Article Synopsis
- Negative pressure pulmonary edema (NPPE) occurs when a rapid drop in pressure in the chest cavity leads to fluid buildup in the lungs, often due to airway blockages, and can cause severe breathing problems.
- This case study highlights a young female patient's experience with NPPE after undergoing surgery for an ectopic pregnancy, where she faced a sudden drop in oxygen levels and breathing difficulties right after being taken off the ventilator.
- The medical team responded quickly with treatments like oxygen therapy and medications, resulting in her recovery and discharge from the hospital after six days of care.
Investigating the effects of pressure support ventilation and positive end-expiratory pressure during extubation on respiratory system complications.
Perioper Med (Lond)
December 2024
Department of Anesthesiology, Eskisehir Osmangazi University Medical Faculty, Odunpazarı, Eskisehir, 26040, Türkiye.
Background: Postoperative extubation is a critical phase. Various medications and different ventilation modes are employed during extubation to minimize potential issues. This study aimed to observe the early effects of the concurrent use of positive end-expiratory pressure (PEEP) and pressure support ventilation (PSV) modes during the extubation-emerge period on the respiratory system.
View Article and Find Full Text PDFProlonged weaning from mechanical ventilation: who, what, when and how?
Breathe (Sheff)
October 2024
Lane Fox Respiratory Service, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Weaning from invasive mechanical ventilation is an important part of the management of respiratory failure patients. Patients can be classified into those who wean on the first attempt (simple weaning), those who require up to three attempts (difficult weaning) and those who require more than three attempts (prolonged weaning). The process of weaning includes adequately treating the underlying cause of respiratory failure, assessing the readiness to wean, evaluating the response to a reduction in ventilatory support, and eventually liberation from mechanical ventilation and extubation or decannulation.
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