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Utility of photon-counting detectors for MV-kV dual-energy computed tomography imaging.
J Med Imaging (Bellingham)
December 2024
University of Chicago, Department of Radiology, Chicago, Illinois, United States.
Purpose: High soft-tissue contrast imaging is essential for effective radiotherapy treatment. This could potentially be realized using both megavoltage and kilovoltage x-ray sources available on some therapy treatment systems to perform "MV-kV" dual-energy (DE) computed tomography (CT). However, noisy megavoltage images obtained with existing energy-integrating detectors (EIDs) are a limiting factor for clinical translation.
View Article and Find Full Text PDFThe TROG 15.01 stereotactic prostate adaptive radiotherapy utilizing kilovoltage intrafraction monitoring (SPARK) clinical trial database.
Med Phys
November 2024
Image X Institute, The University of Syndey, Sydney, Australia.
Article Synopsis
- * The SPARK trial was a phase II study involving 48 patients that utilized KIM technology to monitor real-time tumor movements and evaluate the accuracy of cancer targeting during radiotherapy.
- * The publicly available dataset includes a variety of imaging and treatment data, stored at the University of Sydney eScholarship Repository, which can be used for further research and analysis in the field of radiotherapy.
A radiation therapy platform to enable upright cone beam computed tomography and future upright treatment on existing photon therapy machines.
Med Phys
November 2024
Department of Physical Science, Peter MacCallum Cancer Centre, Melbourne, Australia.
Background: The conventional lying down position for radiation therapy can be challenging for patients due to pain, swallowing or breathing issues. To provide an alternative upright treatment position for these patients, we have developed a portable rotating radiation therapy platform which integrates with conventional photon treatment machines. The device enables cone-beam computed tomography (CBCT) imaging of patients in an upright position, and the future delivery of therapeutic radiation.
View Article and Find Full Text PDFImpact of deep inspiration breath hold, surface-guided radiotherapy, and daily CBCT on the organs at risk in breast cancer radiotherapy.
Sci Rep
November 2024
Department of Radiation Oncology, Jiahui International Cancer Center Shanghai, Jiahui Health, Shanghai, China.
The goal of the study was to assess the impact of deep inspiration breath hold technique (DIBH), surface-guided radiotherapy (SGRT), and daily kilovoltage cone-beam computed tomography (kV-CBCT) on the dose to organs at risk (OAR) in left-sided breast cancer radiotherapy. Twenty-six consecutive left-sided breast cancer patients treated using Volumetric Intensity Modulated Arc Therapy (VMAT), DIBH, SGRT, and a hypofractionated regimen were retrospectively evaluated in this study. Dose parameters were extracted from dose-volume histograms (DVH).
View Article and Find Full Text PDFTreating a Refractory Locally Advanced Carcinoma of the Cervix With Cone-Beam Computed Tomography-Based Adaptive External Beam Radiotherapy: A Case Report.
Cureus
September 2024
Radiation Oncology, Meherbai Tata Memorial Hospital, Jamshedpur, IND.
Adaptive radiotherapy (ART) refers to methods that allow a radiation therapy plan to be adjusted based on images obtained during the treatment. Using cutting-edge imaging methods such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), ART can adjust the treatment plan in response to observed changes in anatomy and even biology while the patient is receiving treatment. The backbone of ART is intensity-modulated RT (IMRT), which permits better sparing of normal critical organs while still delivering a uniform dose to target tumor volume.
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