Novel coronavirus SARS-CoV-2 has created unprecedented healthcare challenges. Neurologic deficits are often an important presenting symptom. To date, the only reported post-infectious COVID-19 manifestations of neurologic disease include cognitive deficits and dysfunction of the peripheral nervous system. Here we report that seizure can also be a post-COVID-19 or "long-COVID" complication. We present a 71-year-old man with hypertension, diabetes mellitus, and COVID-19 diagnosed by RT-PCR who initially presented with posterior circulation stroke-like symptoms, which completely resolved after emergent thrombolysis. Six days later, the patient returned with seizure activity, supported by radiographic and electroencephalographic studies. Notably, he was negative for SARS-CoV-2, and no other provoking factor was uncovered after a comprehensive work-up. To our knowledge, this is the first report of post-infectious seizures after a case of COVID-19, highlighting the potential importance of monitoring for neurologic symptoms in COVID-19 patients, even after convalescence.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053221 | PMC |
| http://dx.doi.org/10.1016/j.ensci.2021.100340 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Unveiling post-COVID-19 Rasmussen's encephalitis: a case report of rare neurological complication.
Ann Med Surg (Lond)
October 2024
Department of Internal Medicine, Rawalpindi Medical University, Rawalpindi.
Introduction And Importance: Rasmussen encephalitis (RE) is a rare autoimmune disorder that causes unilateral inflammation of the cerebral cortex and can lead to drug-resistant epilepsy and progressive neurological decline. Although the emergence of RE following COVID-19 has not been well documented, it emphasizes the need to understand the impact of COVID-19 on neurological health. This case emphasizes the importance of early recognition and intervention to prevent adverse outcomes related to post-COVID-19 neurological complications.
View Article and Find Full Text PDFComparison of characteristics of children hospitalized for respiratory syncytial virus infection during the pre- and post-COVID-19 eras: a multicenter retrospective study.
BMC Infect Dis
September 2024
Department of Pulmonary and Critical Care Medicine, Yunnan Key Laboratory of Children's Major Disease Research, Yunnan Medical Center for Pediatric Diseases, Kunming Children's Hospital, Kunming Medical University, No. 28, Shulin Street, Xishan District, Kunming, 650034, China.
Article Synopsis
- Respiratory syncytial virus (RSV) has seen a surge in cases among children following the relaxation of COVID-19 restrictions, prompting a study in Yunnan, China to assess differences in RSV infection characteristics pre- and post-COVID-19.
- The research included 2553 pediatric patients, analyzing various data, including demographics and clinical symptoms to identify factors associated with severe lower respiratory tract infection (SLRTI) across the two periods.
- Findings revealed a shift in RSV seasonal patterns and an increase in severe cases, older patient age, and higher clinical and laboratory indicators in post-COVID-19 children compared to those admitted before the pandemic.
A novel combined nomogram for predicting severe acute lower respiratory tract infection in children hospitalized for RSV infection during the post-COVID-19 period.
Front Immunol
August 2024
Department of Pulmonary and Critical Care Medicine, Yunnan Key Laboratory of Children's Major Disease Research, Yunnan Medical Center for Pediatric Diseases, Kunming Children's Hospital, Kunming Medical University, Kunming, Yunnan, China.
Introduction: Off-season upsurge of respiratory syncytial virus (RSV) infection with changed characteristics and heightened clinical severity during the post-COVID-19 era are raising serious concerns. This study aimed to develop and validate a nomogram for predicting the risk of severe acute lower respiratory tract infection (SALRTI) in children hospitalized for RSV infection during the post-COVID-19 era using machine learning techniques.
Methods: A multicenter retrospective study was performed in nine tertiary hospitals in Yunnan, China, enrolling children hospitalized for RSV infection at seven of the nine participating hospitals during January-December 2023 into the development dataset.
Article Synopsis
- Several studies show an increase in neurological and psychiatric problems after COVID-19, including symptoms like depression, anxiety, and seizures, as well as strokes.
- Creutzfeldt-Jakob disease (CJD) has been linked to COVID-19, with most cases emerging weeks to months post-infection, raising concerns about possible connections to neurodegenerative diseases.
- An 83-year-old man with a history of COVID-19 exhibited memory loss and cognitive decline, rapidly worsening and eventually being diagnosed with probable CJD, highlighting the need for further research on post-COVID neurological issues.
Anti-LGI-1 Limbic Encephalitis and Autoimmune Epilepsy Following a Third Dose of COVID-19 Vaccination: A Case Report.
Neurohospitalist
July 2024
Department of Neurology, Royal Victoria Hospital, Belfast, UK.
Anti-leucine rich glioma inactivated 1 (LGI-1) autoimmune encephalitis (AE) typically presents with cognitive impairment, faciobrachial dystonic seizures (FBDS) and hyponatraemia. Reports are growing of neurological complications following coronavirus disease 2019 (COVID-19) vaccination. Here we describe a 50 year old man who developed anti-LGI-1 limbic encephalitis and autoimmune epilepsy 4 days following a dose of the mRNA Pfizer COVID-19 vaccine (of note, his first two vaccinations were viral vector ChAdOX1-S).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!