Clival prolactinoma masquerading as a chordoma: a case report.

Radiol Case Rep

Department of Endocrinology & Diabetes, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

Published: June 2021

Ectopic pituitary adenomas are a rare clinical entity and are frequently mistaken for other base of skull lesions on imaging. We report the clinical presentation and management of a woman presenting with an ectopic prolactinoma located in the clivus. A 66-year-old female presented with a 6-month history of headaches and light-headedness. Anatomical imaging demonstrated a clival lesion most suspicious for chordoma. Endocrinological assessment revealed modestly increased prolactin level with lower-than-expected gonadotrophins levels for her age. Surgical resection confirmed an ectopic prolactinoma. A skull base lesion in a patient with hormonal derangement should lend to a high clinical suspicion of an EPA as they may be treated with medications before surgery. Guidelines could assist clinicians investigating skull-based lesions to identify the rare, but important diagnosis of ectopic pituitary adenomas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8053778PMC
http://dx.doi.org/10.1016/j.radcr.2021.02.071DOI Listing

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