Review of the neurological aspects of HIV infection.

J Neurol Sci

Department of Neurology, The Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Inkosi Albert Luthuli Central Hospital, Private Bag X03, Mayville, 4058 Durban, South Africa. Electronic address:

Published: June 2021

AI Article Synopsis

  • Nearly 40 million people globally are living with HIV, which can lead to serious neurological issues despite improvements in anti-retroviral therapy (ART).
  • This review categorizes neurological disorders related to HIV, distinguishing between those caused directly by the virus and those from opportunistic infections.
  • It highlights the challenges faced in the developing world, where complications from HIV and infections like tuberculosis, toxoplasmosis, and cryptococcal meningitis are still common.

Article Abstract

There are almost 40 million people in the world who live with the human immunodeficiency virus (HIV). The neurological manifestations associated with HIV contribute to significant morbidity and mortality despite the advances made with anti-retroviral therapy (ART). This review presents an approach to classification of neurological disorders in HIV, differentiating diseases due to the virus itself and those due to opportunistic infection. The effects of antiretroviral therapy are also discussed. The emphasis is on the developing world where advanced complications of HIV itself and infections such as tuberculosis (TB), toxoplasmosis and cryptococcal meningitis remain prevalent.

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Source
http://dx.doi.org/10.1016/j.jns.2021.117453DOI Listing

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