AI Article Synopsis
- Tandem catalysis allows for the quick creation of complex structures from basic components, enhancing efficiency in chemical reactions.
- The text discusses integrating stereoselective hydrogenation with other processes like isomerization and oxidation to tackle various challenges in synthesis.
- It emphasizes recent advancements in asymmetric hydrogenation and the potential for using tandem hydrogenation in producing natural products from prochiral starting materials.
Article Abstract
Tandem catalysis enables the rapid construction of complex architectures from simple building blocks. This Perspective shares our interest in combining stereoselective hydrogenation with transformations such as isomerization, oxidation, and epimerization to solve diverse challenges. We highlight the use of tandem hydrogenation for preparing complex natural products from simple prochiral building blocks and present tandem catalysis involving transfer hydrogenation and dynamic kinetic resolution. Finally, we underline recent breakthroughs and opportunities for asymmetric hydrogenation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9141585 | PMC |
| http://dx.doi.org/10.1021/jacs.1c00750 | DOI Listing |
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