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Performance analysis of a wavy fin-and-tube automobile radiator operating on ethylene glycol and water based ternary nanofluids.
Heliyon
January 2025
Operational Research Center in Healthcare, Near East University, TRNC Mersin 10, Nicosia, 99138, Turkey.
Efficient thermal management is crucial for optimizing the performance and longevity of automotive engines, particularly as environmental regulations become more stringent and consumer demand for fuel efficiency increases. This paper investigates the energy and exergy performance of a wavy fin-and-tube radiator employing novel ternary nanofluids (TNFs) for enhanced automotive cooling. A theoretical comparative analysis was performed on four distinct ethylene glycol-water solution-based TNF configurations.
View Article and Find Full Text PDFTryptophan 2,3-dioxygenase-positive matrix fibroblasts fuel breast cancer lung metastasis via kynurenine-mediated ferroptosis resistance of metastatic cells and T cell dysfunction.
Cancer Commun (Lond)
November 2024
Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, P. R. China.
Background: Tumor metastasis is a major threat to cancer patient survival. The organ-specific niche plays a pivotal role in tumor organotropic metastasis. Fibroblasts serve as a vital component of the metastatic microenvironment, but how heterogeneous metastasis-associated fibroblasts (MAFs) promote organotropic metastasis is poorly characterized.
View Article and Find Full Text PDFPlatelet bioenergetic profiling uncovers a metabolic pattern of high dependency on mitochondrial fatty acid oxidation in type 2 diabetic patients who developed in-stent restenosis.
Redox Biol
June 2024
Department of Clinical Laboratory, Key Clinical Laboratory of Henan Province, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, Henan, China.
Although platelet bioenergetic dysfunction is evident early in the pathogenesis of diabetic macrovascular complications, the bioenergetic characteristics in type 2 diabetic patients who developed coronary in-stent restenosis (ISR) and their effects on platelet function remain unclear. Here, we performed platelet bioenergetic profiling to characterize the bioenergetic alterations in 28 type 2 diabetic patients with ISR compared with 28 type 2 diabetic patients without ISR (non-ISR) and 28 healthy individuals. Generally, platelets from type 2 diabetic patients with ISR exhibited a specific bioenergetic alteration characterized by high dependency on fatty acid (FA) oxidation, which subsequently induced complex III deficiency, causing decreased mitochondrial respiration, increased mitochondrial oxidant production, and low efficiency of mitochondrial ATP generation.
View Article and Find Full Text PDFAssessment of wound healing activity in diabetic mice treated with a novel therapeutic combination of selenium nanoparticles and platelets rich plasma.
Sci Rep
March 2024
National Institute of Laser Enhanced Sciences, Cairo University, Giza, 12613, Egypt.
Diabetic wound healing is sluggish, often ending in amputations. This study tested a novel, two-punch therapy in mice-Selenium nanoparticles (Se NPs) and platelet-rich plasma (PRP)-to boost healing. First, a mouse model of diabetes was created.
View Article and Find Full Text PDFEffect of Surface Chemistry on Hemolysis, Thrombogenicity, and Toxicity of Carbon Nanotube Doped Thermally Sprayed Hydroxyapatite Implants.
ACS Biomater Sci Eng
March 2024
Surface Engineering Laboratory, Department of Mechanical Engineering, National Institute of Technology Karnataka, Srinivasnagar, Surathkal 575025, India.
Assessing blood compatibility is crucial before in vivo procedures and is considered more reliable than many in vitro tests. This study examines the physiochemical properties and blood compatibility of bioactive powders ((0.5-2 wt % carbon nanotube (CNT)/alumina)-20 wt %)) produced through a heterocoagulation colloidal technique followed by ball milling with hydroxyapatite (HAp).
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