AI Article Synopsis
- The study investigated how to predict prenatal complications and surgical options for fetuses diagnosed with exomphalos based on a review of 41 cases from 2007 to 2017.
- Out of the examined fetuses, a significant number (39 cases) resulted in various outcomes, including terminations and live births, with karyotyping revealing a high rate of abnormalities.
- The research found that the maximal diameter of the exomphalos compared to the abdomen circumference (EDmax/AC-ratio) is an effective parameter for predicting successful postnatal surgical closure, particularly when the ratio is above 0.24.
Article Abstract
The aim of this study was to detect a parameter for predicting prenatal complications or postnatal surgical options after detecting a fetal exomphalos. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 41 cases of exomphalos in between 2007 and 2017, considering the measurement of ratios. The 41 fetuses with exomphalos were examined, 34 cases (82.9%) with karyotyping and 16 cases (39%) with an abnormal karyotype. Outcome of 39 cases showed 6 abortions (15.4%), 15 terminations (38.5%), an intrauterine fetal death (2.5%) and 17 alive babies (43.6%), which were grouped in two: small exomphalos (n = 6, 35.3%) and big exomphalos (n = 11, 64.7%). Maximal diameter of exomphalos/abdomen circumference-ratio (EDmax/AC-ratio) with a cut-off of 0.24 showed a better predictive value of postnatal primary closure. Exomphalos is correlated with abnormal karyotype. EDmax/AC-ratio gives the best prediction for postnatal primary closure of the defect.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062495 | PMC |
| http://dx.doi.org/10.1038/s41598-021-88245-0 | DOI Listing |
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