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Emergence and clinical challenges of ST11-K64 carbapenem-resistant Klebsiella pneumoniae: molecular insights and implications for antimicrobial resistance and virulence in Southwest China.
BMC Infect Dis
January 2025
Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Background: In clinical practice, the emergence of ST11-K64 carbapenem-resistant Klebsiella pneumoniae (ST11-K64 CRKP) has become increasingly alarming. Despite this trend, limited research has been conducted to elucidate the clinical and molecular characteristics of these strains.
Objectives: This study aimed to comprehensively investigate the clinical characteristics, antimicrobial resistance patterns, resistance and virulence-associated genes, and molecular epidemiology of ST11-K64 CRKP in Southwest China.
Management of Posterior Glottic Stenosis: A Systematic Review.
J Voice
December 2024
Division of Laryngology and Bronchoesophagology, Department of Otolaryngology Head Neck Surgery, EpiCURA Hospital, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Phonetics and Phonology Lab, CNRS UMR7018, Sorbonne University, Paris, France; Department of Otolaryngology, Elsan Hospital, Paris, France. Electronic address:
Objective: To review the current literature about surgical management and postoperative outcomes of posterior glottic stenosis (PGS).
Data Sources: PubMED, Scopus, and Cochrane Library.
Methods: Three investigators conducted a comprehensive review of the literature related to the epidemiology, etiologies, and management of adult patients with PGS through the PRISMA statements.
[End of life perspectives: a systematic survey of patients with amyotrophic lateral sclerosis].
Nervenarzt
December 2024
Ambulanz für ALS und andere Motoneuronerkrankungen, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland.
Background: Amyotrophic lateral sclerosis (ALS) is a disease that still has to be primarily treated symptomatically or palliatively. It is therefore all the more important, in addition to initiating treatment, such as percutaneous endoscopic gastrostomy (PEG), noninvasive ventilation therapy (NIVT) and invasive ventilation therapy via tracheotomy (IVT), to discuss the possible termination of these measures early on.
Question: What is the importance of advance directives for those affected and where are possible deficits in therapy planning for the end of life?
Material And Method: Between March 2017 and January 2019 patients with a clinically confirmed diagnosis of ALS at six treatment centers were asked to fill out a questionnaire.
Submucosal Thyroarytenoid Myectomy with Arytenoidectomy in Treating Bilateral Vocal Fold Immobility.
Laryngoscope
November 2024
Division of Otolaryngology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Article Synopsis
- Surgery for bilateral vocal fold immobility (BVFI) seeks to improve airway function while maintaining voice and swallowing capabilities, and current methods often result in challenging healing outcomes and granulation tissue issues.
- A case-series analysis of eight BVFI patients who underwent a new surgical technique showed successful decannulation rates and improved respiratory symptoms without negatively impacting long-term voice or swallowing functions.
- The proposed method, submucosal thyroarytenoid myomectomy with arytenoidectomy, effectively utilizes body’s natural healing processes while preserving important laryngeal structures, enhancing overall treatment effectiveness for BVFI.
Three Cases of Immune Myocarditis Associated with Camrelizumab Use.
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September 2024
Department of Pharmacy, Provincial Hospital of Shandong First Medical University, Jinan, China.
Introduction: Immune checkpoint inhibitors can cause immune-related adverse events in various organ systems, with myocarditis being the most serious and life-threatening. This article reports three cases of immune myocarditis induced by camrelizumab, detailing the diagnostic and treatment process.
Case Report: Three cases of immune-related myocarditis caused by the use of camrelizumab are reported.
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