AI Article Synopsis
- Cell-free and concentrated ascites reinfusion therapy (CART) involves filtering and concentrating ascitic fluid from patients before reinfusing it intravenously.
- A new machine called Plasauto μ has been evaluated in a clinical study with 17 patients suffering from malignant ascites, demonstrating effective filtration of ascitic fluid.
- The study found that recovery rates for key proteins were acceptable, showing positive results in processing malignant ascites without any reported adverse events related to the machine.
Article Abstract
Cell-free and concentrated ascites reinfusion therapy (CART) is performed by collecting the ascites from the patient, followed by filtration and concentration. Thereafter, concentrated cell-free ascites is reinfused into the patient intravenously. The new type of machine, Plasauto μ, for managing the process of CART was launched onto the market. We have evaluated the machine through postmarketing clinical study in 17 patients with malignant ascites. The amounts of original and concentrated ascites were 3673 ± 1920 g and 439 ± 228 g, respectively. Recovery rates were acceptable regarding values of total protein, albumin, and IgG that were 55.6% ± 17.3%, 60.2% ± 20.8%, and 58.2% ± 20.5%, respectively. Recovery rates were positively associated with amounts of original ascites and negatively associated with total protein concentration. No adverse events related to the machine were observed. The new type of machine showed preferable performance in processing malignant ascites.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359940 | PMC |
| http://dx.doi.org/10.1111/1744-9987.13658 | DOI Listing |
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