Background: The present study determined the incidence of rifampicin resistance among outpatients at the General Hospital Yauri, Kebbi State, Nigeria.
Materials And Methods: The study is a cross-sectional study conducted from February 2018 to October 2019. Sociodemographic data were collected from hospital registration books. Rifampicin resistance was detected using GeneXpert Model GX-IV following manufacturers' instruction. Descriptive statistics and logistic regression were computed using SPSS version 20. The results were presented as odds ratios with associated 95% confidence intervals, and P-value at 0.05.
Result: Of the 837 samples, 65.8% (551/837) were males, and 34.2% (286/837) females, 11.4% (95/837) HIV-seropositive. was detected in 15.5% (130/837), of which 116/130 (89.23%) were males and 14/130 (10.77%) females. -HIV coinfection was detected in 9.47% (9/95) of HIV positive. Rifampicin resistance was observed in 1.3% (11/837), 7.7% (10/130) in patients and 1.05% (1/94) in HIV seropositive. In logistic regression, the odds ratio for having a rifampicin-resistant was 0.49 (0.15-1.54) for > 30 years; taking <30 years as the reference value, 1.02 (1.00-1.03) for male; taking female as the reference value, and 0.78 (0.09-6.15) for HIV positive, taking negative as the reference value.
Conclusion: This study reported the current incidence rate of rifampicin-resistant at the General Hospital Yelwa Yauri, Kebbi State, Nigeria, among presumptive TB patients. Patients diagnosed with rifampicin-resistant were predominantly male adults. Thus, frequent screening is vital for surveillance and reduces the risk of transmission and spread of infections.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047284 | PMC |
| http://dx.doi.org/10.21010/ajid.v15i1.6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cappable-seq RNA-sequencing data sets of K-12 MG1655 treated with novobiocin, tetracycline, and rifampicin.
Microbiol Resour Announc
December 2024
Research Department for Limnology, Mondsee, Universität Innsbruck, Mondsee, Austria.
Mapping transcription start sites and determining their activity remain a challenging task even for well-studied organisms. Here, we present Cappable-seq RNA sequencing data of K-12 MG1655 after treatment with three antibiotics with various spectra of action that may expand the range of mapped transcription start sites for this model organism.
View Article and Find Full Text PDFRibosome engineering of Myxococcus xanthus for enhancing the heterologous production of epothilones.
Microb Cell Fact
December 2024
State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, 266237, People's Republic of China.
Background: Ribosome engineering is a semi-empirical technique used to select antibiotic-resistant mutants that exhibit altered secondary metabolism. This method has been demonstrated to effectively select mutants with enhanced synthesis of natural products in many bacterial species, including actinomycetes. Myxobacteria are recognized as fascinating producers of natural active products.
View Article and Find Full Text PDFAntibiotic susceptibility testing and molecular characterization based on whole-genome sequencing of isolates from pediatric infections at the National Regional Medical Center of Southwest China during the COVID-19 pandemic.
Front Public Health
December 2024
Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Background: is a transmitted respiratory pathogen that causes high morbidity and mortality in children, especially those under 5 years of age. During the implementation of population control measures for COVID-19 in mainland China, the detection rate in pediatric patients decreased. However, with the second wave of the COVID-19 pandemic (2022), the incidence of pneumococcal disease (PD) and even invasive pneumococcal disease (IPD) began to rise again.
View Article and Find Full Text PDF[Study on drug resistance and molecular typing of food-borne Staphylococcus aureus in Ningxia, 2011-2022].
Wei Sheng Yan Jiu
November 2024
Ningxia Hui Autonomous Region Center for Disease Control and Prevention, Yinchuan 750004, China.
Objective: To investigate the molecular typing characteristics, drug resistance status and drug resistance gene carrying of food-borne Staphylococcus aureus in Ningxia.
Methods: Staphylococcus aureus isolated from food safety risk monitoring project in Ningxia in the past ten years were collected, drug resistance was detected using microbroth dilution method, enterotoxins were detected by real-time PCR. The strains were genotyped by pulsed field gel electrophoresis(PFGE) using SmaI endonuclease.
Tuberculous pericarditis in a 71-year-old immunocompetent patient: Case report.
IDCases
November 2024
Doctor of Medicine and Surgery, Hospital Escuela Universitario, Honduras.
Tuberculosis is a transmissible disease caused by the bacterium . It is the leading cause of mortality due to infectious diseases. Tuberculous pericarditis is one of the manifestations of extrapulmonary tuberculosis and represents the primary cause of pericardial effusion in developing countries.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!