[Scurvy. A reminder].

Tidsskr Nor Laegeforen

Published: June 1988

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Scurvy.

Acta Dermatovenerol Croat

July 2022

Ivan Krečak, MD, PhD, Department of Internal Medicine, General Hospital of Šibenik-Knin County, Stjepana Radića 83, 22000 Šibenik, Croatia;

Dear Editor, Scurvy is a nutritional disorder which can develop after prolonged (>1-3 months) severe vitamin C deficiency. Vitamin C is a cofactor in several enzyme reactions involved in collagen synthesis. The defect in collagen causes blood vessel fragility, poor wound healing, mucocutaneous bleedings, hair abnormalities, bone pains, and joint contractures due to periosteal and intraarticular bleeding (1,2).

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Nutrition and art: 19th century images of scurvy, chlorosis, and pellagra.

Clin Dermatol

November 2021

Private Practice, Pembroke Pines, Florida, USA. Electronic address:

Epidemics of nutritional deficiency disorders, caused by a lack of vitamins and minerals, were once very common and claimed many victims. Fortunately, advances in medicine have led to improved diets and a decline in the incidence of these disorders so that they are now seen clinically less often. Reminders of diseases such as scurvy, chlorosis, and pellagra can be found in artwork from the 19th century.

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Scurvy is a disease caused by vitamin C deficiency, historically associated with long sea voyages, periods of famine and war. Currently, it is often misdiagnosed and underreported, as physicians tend to consider it a disease of the past. We present the case of a 79-year-old female who was admitted to the Emergency Department complaining of pruritus.

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Now you C me: a case of scurvy presenting as depression and anaemia.

BMJ Case Rep

March 2020

Department of General Medicine, Monash Health, Clayton, Victoria, Australia.

A 66-year-old Caucasian woman was admitted with deteriorating mental health in the setting of background history of schizophrenia and depression. Her husband reported that she had increasing negative thoughts and decreased motivation regarding her self-care over a few weeks with no obvious stressors. Initial laboratory tests were unremarkable except for isolated normocytic anaemia.

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Scurvy: Dietary Discretion in a Developed Country.

Clin Pract Cases Emerg Med

May 2018

Wake Forest School of Medicine, Department of Emergency Medicine, Winston-Salem, North Carolina.

Although the causes have changed, scurvy (vitamin C deficiency) is still diagnosed in developed countries. We report a case of an 18-year-old female who presented to our emergency department with thrombocytopenia, sinus tachycardia, hypotension, fatigue, gingival hyperplasia, knee effusion, petechiae and ecchymosis in lower extremities. The differential diagnosis included hematologic abnormalities, infectious etiologies, vasculitis and vitamin deficiency.

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