Purpose: In 2011, the International Commissionon Radiological Protection (ICRP) recommended reducing the threshold dose for the lens. Therefore, it is important to reduce the lens exposure dose in medical exposures. In a cranio-caudal (CC) view of mammography, the patient' s lens receives scattered radiation. In this study, we investigated scatter dose around the lens during mammography and reviewed the simple and easy protection methods of the lens.
Methods: Optically stimulated luminescence (OSL) dosimeters were placed in front of the device to obtain scattered radiation intensity distribution. The human phantom was placed in the same way as the CC positioning, and BR-12 phantoms with a thickness of 40 mm was placed on the FPD. Then, the scatter dose around the lens was measured using an OSL dosimeter. In order to confirm the change in the scatter radiation dose by the face guard (FG) and eyelid, we measured and compared under the same conditions the presence of FG and adipose tissue about 1 mm thick assuming the eyelid.
Results: Scatter radiation intensity decreased around the FG. When the FG was installed, the scatter dose was reduced about 33%, and when the adipose tissue was pasted on the OSL dosimeter, the scatter dose was reduced about 29%.
Conclusion: This study suggested that eye closure during mammography was effective in reducing lens exposure. In the future, we would like to expect further protective effects by increasing the thickness of FG and reviewing the materials.
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http://dx.doi.org/10.6009/jjrt.2021_JSRT_77.4.358 | DOI Listing |
Int J Biol Macromol
January 2025
Bach Institute of Biochemistry, Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninsky pr. 33, Moscow 119071, Russia. Electronic address:
UV-irradiation is a stress factor for proteins, leading to disruption of their native structure. Test systems based on UV-irradiated proteins are relevant for researchers, as they allow working directly with damaged protein molecules, which can be important when studying the properties and mechanisms of action of various antiaggregation agents. The study of UV-irradiated proteins can also have applied significance, including medical.
View Article and Find Full Text PDFBiomed Phys Eng Express
January 2025
Department of Medical Physics, Osaka Heavy Ion Therapy Center, Otemae, Chuo-ku, Osaka, Osaka, 5400008, JAPAN.
Objective Applying carbon ion beams, which have high linear energy transfer and low scatter within the human body, to Spatially Fractionated Radiation Therapy (SFRT) could benefit the treatment of deep-seated or radioresistant tumors. This study aims to simulate the dose distributions of spatially fractionated beams (SFB) to accurately determine the delivered dose and model the cell survival rate following SFB irradiation. Approach Dose distributions of carbon ion beams are calculated using the Triple Gaussian Model.
View Article and Find Full Text PDFNanomaterials (Basel)
January 2025
Institute of Scientific Instruments of the Czech Academy of Sciences, Kralovopolska 147, 61200 Brno, Czech Republic.
Phase contrast imaging is well-suited for studying weakly scattering samples. Its strength lies in its ability to measure how the phase of the electron beam is affected by the sample, even when other imaging techniques yield low contrast. In this study, we explore via simulations two phase contrast techniques: integrated center of mass (iCOM) and ptychography, specifically using the extended ptychographical iterative engine (ePIE).
View Article and Find Full Text PDFBiotechnol Appl Biochem
January 2025
Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, Tamil Nadu, India.
Globally, breast cancer continues to be the leading type of cancer affecting women, with rising mortality rates projected by 2030. This highlights the importance of developing new, affordable treatments, like drug delivery systems that use nanoparticles. Gold nanoparticles (AuNPs), including their exceptional optical and physical attributes, make them an attractive vehicle for targeted treatment, allowing for accurate and focused delivery of medication directly to cancerous cells while reducing harmful side effect.
View Article and Find Full Text PDFBMC Cancer
January 2025
Finetech in Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.
Background And Aim: Zinc oxide and copper oxide nanoparticles are known for their promising biological activities. This study aims to synthesize zinc oxide nanoparticles and copper-doped zinc oxide nanoparticles to harness the combined cytotoxic and anticancer effects of them in vitro and in vivo studies.
Methods: Zinc oxide nanoparticles, both doped and undoped, were synthesized using a chemical co-precipitation method.
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