AI Article Synopsis

  • The management of locally advanced rectal cancer has evolved from a standardized treatment approach to a more personalized and multidisciplinary strategy.
  • Recent changes in care involve varying the timing, sequence, duration, and inclusion of different therapies tailored to individual patients.
  • This review highlights important evidence that supports the shift in treatment paradigms for rectal cancer, emphasizing the need for adaptability in patient care.

Article Abstract

The management of locally advanced rectal cancer has grown in both complexity and quality since the first proctectomy. What once was a malignancy with a fairly consistent treatment algorithm for decades, a recent paradigm shift in the care of these patients has led to a more personalized, multidisciplinary approach with variations in timing, sequence, duration, and potential exclusion of multimodality therapies. This review summarizes the most important evidence behind these developing overarching concepts to provide a context for this paradigm shift.

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Source
http://dx.doi.org/10.1200/OP.20.00885DOI Listing

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