Herein, we report a neutral iridium complex, [Ir(4-(2-pyridinyl)benzaldehyde)2(acetylacetone)] (Ir-ER), with viscosity-responsive phosphorescent emission intensity and lifetime. Quantitative measurement by two-photon phosphorescent lifetime imaging shows that the viscosity of ER increases significantly in the process of erastin-induced ferroptosis. Our work provides an effective strategy for quantitative measurement of the micro-environmental alternations of subcellular organelles during a specific cell death process.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d1cc01062j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Making Mo(0) a Competitive Alternative to Ir(III) in Phosphors and Photocatalysts.
J Am Chem Soc
January 2025
Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland.
Iridium is used in commercial light-emitting devices and in photocatalysis but is among the rarest stable chemical elements. Therefore, replacing iridium(III) in photoactive molecular complexes with abundant metals is of great interest. First-row transition metals generally tend to yield poorer luminescence behavior, and it remains difficult to obtain excited states with redox properties that exceed those of noble-metal-based photocatalysts.
View Article and Find Full Text PDFNHC-Based Deep-Red Phosphorescent Iridium Complexes Featuring Three-Charge (0, -1, -2) Ligands.
Inorg Chem
January 2025
School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003, P. R. China.
N-heterocyclic carbene (NHC)-based phosphorescent iridium complexes have attracted extensive attention due to their good optical properties and high stability in recent years. However, currently reported NHC-based iridium complexes can easily achieve emission of blue, green, or even ultraviolet light, while emission of red or deep-red light is relatively rare. Here, we report a new family of NHC-based deep-red iridium complexes (Ir1, Ir2, Ir3, and Ir4) featuring three-charge (0, -1, -2) ligands.
View Article and Find Full Text PDFEarth-abundant transition metal complexes in light-emitting electrochemical cells: successes, challenges and perspectives.
Dalton Trans
January 2025
Normandy University, ENSICAEN, UNICAEN, CNRS, LCMT, 6 Bd du Maréchal Juin, 14050 Caen, France.
Light-emitting electrochemical cells (LECs) are an attractive technology in the field of solid state light devices (SSLDs) as their simple architectures allow the preparation of cost-effective lighting devices. Consequently, low-cost and sustainable emitters are highly desirable. Transition metal complexes are attractive in this field as they have been proved to possess compatible optoelectronic properties.
View Article and Find Full Text PDFMultiple-Signal Amplification Strategy to Fabricate an Ultrasensitive Electrochemiluminescence Magnetic Immunosensor for Detecting Biomarkers of Alzheimer's Disease via Iridium-Based Self-Enhancing Nanoemitters.
ACS Sens
January 2025
School of Chemistry and Life Sciences, Jiangsu Key Laboratory for Environmental Functional Materials, Suzhou University of Science and Technology, Suzhou, Jiangsu 215009, China.
Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive decline, significantly impairing the daily life of elderly individuals. The low abundance of blood-based biomarkers in AD necessitates higher analytical technique requirements. Herein, one novel iridium-based ECL self-enhanced nanoemitter (TPrA@Ir-SiO) was unprecedentedly reported, and it was further used to construct an ultrasensitive ECL magnetic immunosensor by a multiple-signal amplification strategy to unequally sensitively and accurately detect the AD blood-based biomarker (P-tau181) in this work.
View Article and Find Full Text PDFIridium(III) Blue Phosphors with Heteroleptic Carbene Cyclometalates: Isomerization, Emission Tuning, and OLED Fabrications.
Angew Chem Int Ed Engl
January 2025
City University of Hong Kong, Materials Sciences and Engineering, 83 Tat Chee Road, Kowloon, 999077, Kowloon Tong, HONG KONG.
Ir(III) complexes are particularly noted for their excellent photophysical properties in giving blue OLED phosphors. In this study, two distinctive carbene pro-chelates LAH2+ and LBH2+ (or LCH2+) were employed in preparation of heteroleptic Ir(III) complexes, to which LAH2+ bears a cyano substituted benzoimidazolium along with N-mesityl appendage, while LBH2+ (or LCH2+) carries the symmetrical benzoimidazolium entity. Notably, the reversible equilibration at high temperature was observed for m, f-ct14 and m, f-ct15 with a single LA chelate.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!