Neonatal sepsis is one of the most critical illnesses in newborns with significant morbidity and mortality, particularly in developing countries. The present, cross-sectional, hospital-based, study was conducted to evaluate the association of red cell distribution width (RDW) with neonatal sepsis and its role as a predictive marker in the diagnosis of neonatal sepsis at Soba University Hospital, during the period July 2018 to April 2019. The study population was term neonates, aged 1-28 days, who were diagnosed with neonatal sepsis, with positive blood culture. A total of 111 full-term neonates had blood culture proven neonatal sepsis and the majority of them (100%, 90%) had positive C-reactive protein (CRP). The average RDW in this study was 19.3% and was elevated in 103 (92%) of the study participants with a significant association with positive blood culture. The majority (65%, 58.6%) of mothers of the studied neonates did not have an illness during pregnancy, 19 (17.1%) had diabetes mellitus, 9 (8.1%) had hypertension, in addition to other different conditions in 18 (16.2%). The common causes of admission of the studied newborns included respiratory distress (70%, 79%), jaundice (33%, 29.7%) and lethargy (28%, 25.2%). was the most common organism isolated from blood culture in 50 (45.0%) patients, and was the least one, isolated in only one (0.9%) newborn. There is a significant association between positive blood culture, CRP and elevated RDW (-value 0.01). RDW was found to be significantly elevated in the studied newborns with neonatal sepsis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026007PMC
http://dx.doi.org/10.24911/SJP.106-1597237251DOI Listing

Publication Analysis

Top Keywords

neonatal sepsis
28
blood culture
20
positive blood
12
red cell
8
cell distribution
8
distribution width
8
sepsis soba
8
soba university
8
university hospital
8
association positive
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!