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Comparison of CytoSorb and Jafron HA330 Hemoadsorption Devices in Pediatric Oncological Patients with Sepsis: Retrospective Observational Study.
J Clin Med
December 2024
Pediatric Anesthesiology and Intensive Care Unit, Mother and Child Center, "University Medical Center", Astana Z05K4F4, Kazakhstan.
Pediatric sepsis presents a severe risk to immunocompromised children, especially those with cancer or pre-existing conditions, posing a significant threat to their lives. Cytokine hemadsorption has emerged as a promising therapeutic approach for managing sepsis and severe inflammatory conditions in critically ill patients. This innovative method involves eliminating pro-inflammatory cytokines from the bloodstream, targeting the underlying hyper-inflammatory response often seen in critical illnesses.
View Article and Find Full Text PDFNon-Cell-Based Extracorporeal Artificial Liver Systems: Historic Perspectives, Approaches and Mechanisms, Current Applications, and Challenges.
Artif Organs
December 2024
Department of Mechanical Engineering, University of Washington, Seattle, Washington, USA.
Background: Liver disease is a growing burden. Transplant organs are scarce. Extracorporeal liver support systems (ELSS) are a bridge to transplantation for eligible patients.
View Article and Find Full Text PDFHemadsorption with CytoSorb®: focus on the latest experiences in cardiac surgery patients.
J Artif Organs
December 2024
Division of Cardiology, Ospedale Civile Maggiore Borgo Trento, Piazzale Stefani, Verona, (VR), Italy.
Cardiac surgery patients are potentially exposed to an acute inflammatory host response with a huge release of both pro- and anti-inflammatory cytokines both through intrinsic (e.g., tissue damage, endothelial injury) and extrinsic (e.
View Article and Find Full Text PDFObjective: Aim: To analyze the results of the application of extracorporeal detoxification methods in the treatment of drug poisoning and their complications..
Patients And Methods: Materials and Methods: The studied data of 129 patients aged 18-46 years with severe drug poisoning treated at the Kyiv toxicological center in 2010-2020.
Beyond conventional care: The therapeutic potential of hemoperfusion in severe COVID-19.
World J Crit Care Med
December 2024
Faculty of Health Sciences, Kanazawa University, Kanazawa 920942, Japan.
Article Synopsis
- - Hemoperfusion (HP) is a blood purification method used to eliminate toxins and small molecules, proving effective in cases of drug overdose and severe conditions like liver failure and sepsis.
- - A study involving 18 patients with severe COVID-19 showed that HP was well-tolerated and improved respiratory and cardiovascular health, leading to the discharge of 10 patients.
- - Literature analysis of 20 studies with 873 patients also indicated that HP often resulted in better survival rates and clinical outcomes, suggesting a need for more research on its use in critically ill patients with infectious diseases like COVID-19.
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