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ASO Author Reflections: Real-World Results of the KEYNOTE-522 Regimen to Guide Surgical Decision Making.
Ann Surg Oncol
January 2025
Department of Breast Surgery, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, USA.
Raman spectra of pyromorphite, vanadinite and mimetite at high pressures and high temperatures.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Key Laboratory of High-temperature and High-pressure Study of the Earth's Interior, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081 Guizhou, China. Electronic address:
High-pressure and high-temperature Raman spectra of natural pyromorphite, vanadinite and mimetite were measured up to 11 GPa and 973 K, respectively. No phase transition was observed within the temperature and pressure ranges in this study. Raman modes for pyromorphite, vanadinite and mimetite vary with temperature or pressure linearly.
View Article and Find Full Text PDFASO Author Reflections: Enhancing Shared Decision-Making with Risk Prediction Models in Sarcoma Care.
Ann Surg Oncol
January 2025
Orthopedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
ASO Visual Abstract: Surgical Margins and Oncologic Outcomes Following Wedge Resection of Pulmonary Metastases in Pediatric and Young Adult Sarcoma Patients.
Ann Surg Oncol
January 2025
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
APP antisense oligonucleotides are effective in rescuing mitochondrial phenotypes in human iPSC-derived trisomy 21 astrocytes.
Alzheimers Dement
January 2025
Department of Neuroscience, City University of Hong Kong, Hong Kong, Hong Kong.
Introduction: Antisense oligonucleotides (ASOs) have shown promise in reducing amyloid precursor protein (APP) levels in neurons, but their effects in astrocytes, key contributors to neurodegenerative diseases, remain unclear. This study evaluates the efficacy of APP ASOs in astrocytes derived from an individual with Down syndrome (DS), a population at high risk for Alzheimer's disease (AD).
Methods: Human induced pluripotent stem cells (hiPSCs) from a healthy individual and an individual with DS were differentiated into astrocytes.
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