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http://dx.doi.org/10.1186/s12917-021-02858-1 | DOI Listing |
Nat Commun
January 2025
Guangzhou National Laboratory, Guangzhou, 510005, China.
Sports Med
January 2025
IRMES-UPR 7329, Institut de Recherche Médicale et d'Épidémiologie du Sport, Université Paris Cité, 11 Avenue du Tremblay, 75012, Paris, France.
The scientific literature on talent identification is extensive, with significant advancements made over the past 30 years. However, as with any field, the translation of research into practice and its impact on the field have been slower than anticipated. Indeed, recent findings highlight a pervasive relative age effect, the effects of maturation being often overlooked, disparate populations between young and senior performers, and a necessity to embrace a holistic approach.
View Article and Find Full Text PDFBioinformatics
December 2024
Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, United States.
Motivation: Recent advancements in parallel sequencing methods have precipitated a surge in publicly available short-read sequence data. This has encouraged the development of novel computational tools for the de novo assembly of transcriptomes from RNA-seq data. Despite the availability of these tools, performing an end-to-end transcriptome assembly remains a programmatically involved task necessitating familiarity with best practices.
View Article and Find Full Text PDFEur J Med Chem
February 2025
Laboratory of Experimental Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic; Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. Electronic address:
Familial dysautonomia is a debilitating congenital neurodegenerative disorder with no causative therapy. It is caused by a homozygous mutation in ELP1 gene, resulting in the production of the transcript lacking exon 20. The compounds studied as potential treatments include the clinical candidate kinetin, a plant hormone from the cytokinin family.
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