Background: Major Depressive Disorder (MDD) has been shown a high prevalence and debilitating mental health. Most of the burden comes from reduced work functioning and frequent or long-term absenteeism.
Aims: Describe psychosocial functionality in sample of workers with MDD and observe associated factors with sick-leave.
Methods: Cross-sectional study. Participants were 172 formal workers with MDD according to Mini International Neuropsychiatric Interview. They were classified as active ( = 76) or in sick leave ( = 96). Functionality Assessment Short Test (FAST) was used and the variables were: personal, clinical, and occupational characteristics. Descriptive, bivariate and hierarchical multivariate analyses were conducted; significant with < .05.
Results: Most of the sample was female and 50. Workers in sick leave were older, less physically active, and presented worse scores in global and in each domain of functionality (FAST). High autonomy at working process, perceived stressing work, do not enjoy the work and low resilience to work adversities were significantly associated with sick leave ( < .05). Regarding clinical characteristics of MDD, severity, clinical comorbidity and recidivate subtype were associated with sick leave outcome ( < .05).
Conclusion: ick leave is an important indicator of global functionality. Effective strategies to reduce MDD burden ought to involve some perspectives: (1) Diagnosis and efficient treatment; (2) Promotion and monitoring of functionality and rehabilitation programs; (3) Subject-centered actions that help workers cope with adversities, mitigate stress, and increase satisfaction at work.
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http://dx.doi.org/10.1177/00207640211011195 | DOI Listing |
J Cyst Fibros
January 2025
Department of Pediatrics, University of Pittsburgh School Of Medicine, USA.
Background: Males with cystic fibrosis (MwCF) face general and disease-specific sexual and reproductive health (SRH) concerns. Using concept mapping (CM), this study identified the SRH topics valued by members of the CF community.
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Complement Ther Med
January 2025
Department of Psychosocial Rehabilitation, Medical University of Lodz, Poland, Narutowicza 60, 90-136 Lodz, Poland.
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View Article and Find Full Text PDFArq Bras Oftalmol
January 2025
Centro de Referência em Oftalmologia, Universidade Federal de Goiás, Goiânia, GO, Brazil.
Purpose: To determine the influence of strabismus and its surgical correction on the preoperative and postoperative functional and psychosocial aspects of patients being treated at the CEROF/UFG Strabismus Outpatient Clinic.
Methods: This prospective cross-sectional study included 27 patients, aged >7 years that were divided into two groups (<18 years and >18 years). The AS 20 questionnaire is composed of two domains (psychosocial and functional).
JAMA Netw Open
January 2025
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland.
Importance: Sensitivity to environmental stress and adversity may influence lung cancer risk, highlighting a critical link between psychosocial factors and cancer etiology.
Objective: To evaluate whether genetically estimated sensitivity to environmental stress and adversity is associated with lung cancer risk.
Design, Setting, And Participants: Data were obtained from a genome-wide association study identifying 37 independent genetic variants strongly associated with sensitivity to environmental stress and adversity and a cross-ancestry genome-wide meta-analysis from the International Lung Cancer Consortium.
Child Neuropsychol
January 2025
Child Development Center, University Children's Hospital Zurich, Zurich, Switzerland.
Executive function (EF) impairments are prevalent in survivors of neonatal critical illness such as children born very preterm (VPT) or with complex congenital heart disease (cCHD). This paper aimed to describe EF profiles in school-aged children born VPT or with cCHD and in typically developing peers, to identify child-specific and family-environmental factors associated with these profiles and to explore links to everyday-life outcomes. Data from eight EF tests assessing working memory, inhibition, cognitive flexibility, switching, and planning in = 529 children aged between 7 and 16 years was subjected into a latent profile analysis.
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