Weak mixed phase in the mutator model.

Phys Rev E

Science, Mathematics and Technology Cluster, Singapore University of Technology and Design, 8 Somapah Road, S487372 Singapore.

Published: March 2021

We consider the mutator model with unidirected transitions from the wild type to the mutator type, with different fitness functions for the wild types and mutator types. We calculate both the fraction of mutator types in the population and the surpluses, i.e., the mean number of mutations in the regular part of genomes for the wild type and mutator type, which have never been derived exactly. We identify the phase structure. Beside the mixed (ordinary evolution phase with finite fraction of wild types at large genome length) and the mutator phase (the absolute majority is mutators), we find another new phase as well-it has the mean fitness of the mixed phase but an exponentially small (in genome length) fraction of wild types. We identify the phase transition point and discuss its implications.

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Source
http://dx.doi.org/10.1103/PhysRevE.103.032113DOI Listing

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