GSEAplot: A Package for Customizing Gene Set Enrichment Analysis in R.

J Comput Biol

Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA.

Published: June 2021

Gene Set Enrichment Analysis (GSEA) is used to identify differentially expressed gene sets that are enriched for annotated biological functions. The existing GSEA R code is not in the form of a flexible package with analysis and plotting customization options, and the results produced are not generated in the form of R objects. In this study, we introduce the GSEAplot R package with novel functionality for saving relevant information from the analysis to the current R workspace, and we introduce the ability to customize plots and databases. The GSEAplot package provides a novel utility that facilitates the implementation of GSEA R-based in genomics analysis pipelines.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219183PMC
http://dx.doi.org/10.1089/cmb.2020.0426DOI Listing

Publication Analysis

Top Keywords

gseaplot package
12
gene set
8
set enrichment
8
enrichment analysis
8
package novel
8
analysis
5
package customizing
4
customizing gene
4
analysis gene
4
analysis gsea
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!