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Immunoglobulin A Vasculitis in a Patient on Hemodialysis and With a Metastatic Liver Lesion. | LitMetric

AI Article Synopsis

  • A 79-year-old man on hemodialysis developed palpable purpura after having pneumonia, leading to a diagnosis of IgA vasculitis.
  • A skin biopsy revealed leukocytoclastic vasculitis with IgA and C3 deposition, prompting treatment with topical corticosteroids.
  • The patient also had a metastatic liver lesion likely linked to colorectal cancer, raising questions about how pneumonia and the liver lesion may be related to the development of IgA vasculitis.

Article Abstract

We present the case of a 79-year-old man on hemodialysis with immunoglobulin A (IgA) vasculitis. He developed palpable purpura three weeks after having pneumonia. A skin biopsy showed leukocytoclastic vasculitis with IgA and C3 deposition. He received a topical corticosteroid for his IgA vasculitis. He was also diagnosed with a metastatic liver lesion, which was thought to be of colorectal origin because of the elevations in carcinoembryonic antigen and cancer antigen 19-9 levels. The skin biopsy played an important role in the diagnosis of the patient on hemodialysis. Pneumonia and a metastatic liver lesion thought to be from colorectal cancer might be related to the pathogenesis of IgA vasculitis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039865PMC
http://dx.doi.org/10.7759/cureus.13863DOI Listing

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