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http://dx.doi.org/10.3389/fnins.2021.671836 | DOI Listing |
Med Image Anal
December 2024
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, USA; Department of Neuroscience and Biomedical Engineering, Aalto University, Finland; Department of Computer Science, Aalto University, Finland.
Recent years have seen a growing interest in methods for predicting an unknown variable of interest, such as a subject's diagnosis, from medical images depicting its anatomical-functional effects. Methods based on discriminative modeling excel at making accurate predictions, but are challenged in their ability to explain their decisions in anatomically meaningful terms. In this paper, we propose a simple technique for single-subject prediction that is inherently interpretable.
View Article and Find Full Text PDFEur J Neurosci
January 2025
Neural Circuits for Spatial Navigation and Memory, Department of Neuroscience, Institut Pasteur, Université Paris Cité, Paris, France.
Front Neurosci
December 2024
Sherbrooke Connectivity Imaging Lab (SCIL), Computer Science Department, University of Sherbrooke, Sherbrooke, QC, Canada.
Front Neurosci
December 2024
Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Objective: High Angular Resolution Diffusion Imaging (HARDI) models have emerged as a valuable tool for investigating microstructure with a higher degree of detail than standard diffusion Magnetic Resonance Imaging (dMRI). In this study, we explored the potential of multiple advanced microstructural diffusion models for investigating preterm birth in order to identify non-invasive markers of altered white matter development.
Approach: Rather than focusing on a single MRI modality, we studied on a compound of HARDI techniques in 46 preterm babies studied on a 3T scanner at term-equivalent age and in 23 control neonates born at term.
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