AI Article Synopsis

  • Small-cell carcinoma of the colon is a very rare type of tumor, first recorded in 1919, with only around 100 cases reported to date, highlighting its unusual occurrence.
  • The case presented involves sigmoid squamous cell carcinoma that resulted in bowel perforation, with diagnosis confirmed through histopathology after emergency surgery.
  • The report also explores various aspects related to this condition, including its incidence, causes, immunohistological markers, neogenomics, and potential treatment approaches.

Article Abstract

Small-cell carcinoma of the colon is an extremely rare tumour, with poorly understood pathogenesis and unestablished treatment guidelines. The first case was documented in 1919, and only about 100 cases of this condition have been reported to this date. In this case report, we present a case of sigmoid squamous cell carcinoma that eventually led to bowel perforation and was diagnosed on histopathology after emergent surgical intervention. Additionally, we also review the incidence, epidemiology, pathogenesis, immunohistological markers, neogenomics and therapeutic strategies for the same.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055152PMC
http://dx.doi.org/10.1136/bcr-2020-240573DOI Listing

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