In the three-year period ending December 1986, 31 infants followed by the Cleft Palate Team of our institution were evaluated with BERA one or more times. Seventy-four percent presented auditory threshold elevation on initial examination; none was observed to resolve spontaneously in the first year of life. Myringotomy and tympanostomy tube insertion normalized auditory thresholds effectively in most children with serous otitis media. In a few cases, however, recovery required several months. BERA can assist the early detection of children with sensorineural hearing loss. It may also be valuable as an additional consideration in selecting treatment of serous otitis media in these children. Precise guidelines as to the ideal time to perform tympanostomy requires further substantiation of the effects of early hearing loss on speech and language development.
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Clin Pract
January 2025
Department of Neurosurgery, University Hospital, 04103 Leipzig, Germany.
: PTEN hamartoma tumor syndrome (PHTS) has evolved into an umbrella term for a range of syndromes, characterized by loss-of-function variants in the phosphatase and tensin homolog (PTEN) tumor suppressor gene on chromosome 10q23.31. This can result in a lifelong tumor predisposition in patients.
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January 2025
Laboratory for Oral Molecular Biology, Department of Orthodontics and Dentofacial Orthopedics, University of Bern, Freiburgstrasse 3, Bern, 3010, Switzerland.
Background: Epidemiologic data on the number of cleft lip and/or palate (orofacial cleft (OFC)) births in Switzerland are currently sparse. However, this knowledge is essential for better understanding the etiologies underlying the various cleft phenotypes and providing expectant parents with the best possible healthcare planning and counseling.
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BMC Pediatr
January 2025
Research Center for Caries Prevention, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: Parents of children born with cleft lip/palate encounter numerous challenges. This study aims to provide a deeper understanding for authorities to better support these parents by exploring the views and experiences of Iranian parents raising babies with cleft lip/palate through qualitative research.
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Turk J Pediatr
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Department of Plastic Reconstructive and Aesthetic Surgery, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
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View Article and Find Full Text PDFClin Trials
January 2025
Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.
Background/aims: When conducting a randomised controlled trial in surgery, it is important to consider surgical learning, where surgeons' familiarity with one, or both, of the interventions increases during the trial. If present, learning may compromise trial validity. We demonstrate a statistical investigation into surgical learning within a trial of cleft palate repair.
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