AI Article Synopsis
- The ethanol extract from the roots of a specific plant was separated using chromatographic techniques, leading to the discovery of two new aromatic compounds and three previously known ones.
- The structures of these compounds were determined using high-resolution mass spectrometry and various spectroscopic methods like NMR and IR.
- The new compounds were tested for their ability to inhibit α-glucosidase, a potential indicator of hypoglycemic properties, and showed weak activity with specific IC values.
Article Abstract
The ethanol extract of the roots of was subjected to chromatographic fractionation, which result in the isolation and characterization of two new aromatic derivatives 2,3-dihydroxypropyl 2,4-dihydroxy-3,6-dimethylbenzoate () and 2-oxopropyl 3-hydroxy-4-methoxybenzoate (), along with three known compounds pilosulinene A (), pollenfuran B () and (+)-pinoresinol (). Their structures were demonstrated by HRESIMS and spectroscopic methods including NMR and IR. It is worth noting that compound was isolated for the first time from the genus . The potential hypoglycemic properties of compounds were evaluated by measuring their α-glucosidase inhibitory effects. As a result, compounds and showed weak α-glucosidase inhibitory activities with IC values of 154.8 ± 11.0 μM and 24.0 ± 2.2 μM, respectively.[Formula: see text].
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| http://dx.doi.org/10.1080/14786419.2021.1912749 | DOI Listing |
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