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Clinical and translational insights on premature ventricular contractions and PVC-induced cardiomyopathy. | LitMetric

The medical community's understanding of the consequences of premature ventricular contractions (PVCs) and PVC-induced cardiomyopathy has been derived mostly from observational and large population-based studies. Due to the difficulty of predicting the development of PVC-cardiomyopathy, the acute and chronic cardiac effects of PVCs and the mechanism of PVC-cardiomyopathy have been derived from pre-clinical studies with large animal models. Recently, these studies have described myocardial substrates that could potentially increase morbidity and mortality in patients with frequent PVCs and PVC-cardiomyopathy. In this paper, we provide an up-to-date comprehensive review of these pre-clinical and clinical studies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192164PMC
http://dx.doi.org/10.1016/j.pcad.2021.04.001DOI Listing

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