AI Article Synopsis
- * analyzed data from January 2013 to December 2018, matching 40 IAI-CPE cases with 120 controls suffering from infections caused by non-resistant bacteria.
- * Found significant risk factors including prior hospitalization, digestive endoscopy, carbapenem therapy, and aminoglycoside use, indicating patients' susceptibility to IAI-CPE.
Article Abstract
The aim of this study was to identify risk factors for acquisition of intra-abdominal infections (IAI) caused by carbapenemase-producing Enterobacteriaceae (CPE) in surgical patients. A matched case-control study was performed. We included all cases with CPE-related IAI acquired during admission to a general surgery department from January 2013 to December 2018, and they were matched with control subjects with IAI caused by non-resistant bacteria (ratio 1:3). Independent risk factors were obtained by logistic regression. Forty patients with IAI-CPE were matched with 120 control subjects. Independent risk factors for acquisition of IAI-CPE were previous hospitalization (odds ratio [OR] 2.56; 95% confidence interval [CI] l 1.01-6.49; p = 0.047), digestive endoscopy (OR 4.11; 95% CI 1.40-12.07; p = 0.010), carbapenem therapy (OR 9.54; 95% CI 3.33-27.30; p < 0.001), and aminoglycoside use (OR 45.41; 95% CI 7.90-261.06; p < 0.001). Four clinical factors can identify patients at high-risk of IAI-CPE.
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| http://dx.doi.org/10.1089/sur.2020.472 | DOI Listing |
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