Out of equilibrium, a lack of reciprocity is the rule rather than the exception. Non-reciprocity occurs, for instance, in active matter, non-equilibrium systems, networks of neurons, social groups with conformist and contrarian members, directional interface growth phenomena and metamaterials. Although wave propagation in non-reciprocal media has recently been closely studied, less is known about the consequences of non-reciprocity on the collective behaviour of many-body systems. Here we show that non-reciprocity leads to time-dependent phases in which spontaneously broken continuous symmetries are dynamically restored. We illustrate this mechanism with simple robotic demonstrations. The resulting phase transitions are controlled by spectral singularities called exceptional points. We describe the emergence of these phases using insights from bifurcation theory and non-Hermitian quantum mechanics. Our approach captures non-reciprocal generalizations of three archetypal classes of self-organization out of equilibrium: synchronization, flocking and pattern formation. Collective phenomena in these systems range from active time-(quasi)crystals to exceptional-point-enforced pattern formation and hysteresis. Our work lays the foundation for a general theory of critical phenomena in systems whose dynamics is not governed by an optimization principle.
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http://dx.doi.org/10.1038/s41586-021-03375-9 | DOI Listing |
Soft Matter
January 2025
Department of Physics, Central University of Karnataka, Kadaganchi, Kalaburagi, Karnataka-585367, India.
The isomerization kinetics of a liquid crystalline azobenzene dimer, comprising cyanoazobenzene and naphthalene (NAZ6), were investigated at the air-water interface. The Langmuir monolayers of NAZ6 in both its and states were analyzed using surface manometry techniques. The results revealed that NAZ6 molecules in the -state displayed the coexistence of a disordered liquid-expanded phase and an ordered liquid-condensed phase, whereas no such phase transition was observed in the -state.
View Article and Find Full Text PDFJ Chem Phys
January 2025
School of Chemistry, University of Lincoln, Brayford Pool, LN6 7TS Lincoln, United Kingdom.
We analyzed the thermal, structural, and dynamic properties of maghemite using classical molecular dynamics, focusing on bulk and nanoparticle systems. We explored their behavior when heated to high temperatures (above the melting point) and during cooling, as well as under thermal cycles ending at intermediate temperatures. Our findings show that in the bulk system, both the tetrahedral and octahedral iron sub-lattices undergo a phase transition prior to melting.
View Article and Find Full Text PDFJ Med Virol
February 2025
Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Epstein-Barr virus (EBV) infection is closely associated with the development of various tumors such as lymphomas and epithelial cancers. EBV has a discrete life cycle with latency and lytic phases. In recent years, significant progress has been made in the understanding of the mechanism underlying the transition of EBV from latency to lytic replication.
View Article and Find Full Text PDFKIF1A, a neuron-specific Kinesin-3 motor, is indispensable for long-distance axonal transport and nuclear migration, processes vital for neuronal function. Using MINFLUX tracking, we reveal that KIF1A predominantly adopts a two-heads-bound state, even under ATP-limiting conditions, challenging prior models proposing a one-head-bound rate-limiting step. This two-heads-bound conformation, stabilized by interactions between the positively charged K-loop and negatively charged tubulin tails, enhances microtubule affinity and minimizes detachment.
View Article and Find Full Text PDFIntegration of DNA replication with DNA repair, cell cycle progression, and other biological processes is crucial for preserving genome stability and fundamentally important for all life. Ataxia-telangiectasia mutated and RAD3-related (ATR) and its partner ATR-interacting protein (ATRIP) function as a critical proximal sensor and transducer of the DNA Damage Response (DDR). Several ATR substrates, including p53 and CHK1, are crucial for coordination of cell cycle phase transitions, transcription, and DNA repair when cells sustain DNA damage.
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