A large-scale snapshot of intratumor heterogeneity in human cancer.

Cancer Cell

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea. Electronic address:

Published: April 2021

Using sophisticated statistical analyses on population-scale cancer whole-genome sequences, a new study published in Cell characterizes the genomic architecture of intratumor heterogeneity (ITH). It results in an unprecedented snapshot of subclones in about 30 cancer types, generating a wealth of insight into the underlying mutational events, processes, and their selection.

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http://dx.doi.org/10.1016/j.ccell.2021.03.005DOI Listing

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