C3dg Quantification by PEG Precipitation and or TRIFMA.

Methods Mol Biol

Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Published: June 2021

AI Article Synopsis

  • There are various methods for detecting complement activation products, but no universal standard exists for clinical measurement.
  • The text outlines a modified assay for measuring C3dg, which is a component related to complement activation.
  • This modified assay is highlighted as simple, inexpensive, and stable, providing an accurate reflection of complement turnover regardless of the activation pathway.

Article Abstract

Detection of complement activation products can be carried out in a number of ways, and different methods are used in different laboratories. No international standard for measuring complement activation in the clinical setting has been agreed upon.Here we describe a modified assay for measuring C3dg. The assay is simple, inexpensive and stable. The estimation of C3dg directly reflects complement turnover independently of activation pathway.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-0716-1016-9_4DOI Listing

Publication Analysis

Top Keywords

complement activation
8
c3dg quantification
4
quantification peg
4
peg precipitation
4
precipitation trifma
4
trifma detection
4
detection complement
4
activation products
4
products carried
4
carried number
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!