Renoprotective activity of a new amide and a new hydroxycinnamic acid derivative from the fresh roots of .

A new amide, named rehmagluamide (), and a new hydroxycinnamic acid derivative, named nepetoidin F (), together with six known compounds, 2'--methyluridine (), puroglutamic acid (), biliverdic acid (), peterolactam (), nicotinic acid (), nicotinamide (), were isolated from the fresh roots of . All the structures of compounds were identified by the interpretation of their spectroscopic data and comparison with those reported in the literatures. The protective effects of compounds on normal rat kidney tubule epithelioid (NRK-52e) cells injury induced by LPS were investigated. The results indicated that compounds , , and exhibited protective effects against LPS-induced NRK 52e cells injury.